Neutrophil to Lymphocyte Ratio Predicts Left Ventricular Remodeling in Patients with ST Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention

Korean Circulation Journal
Abdurrezzak BörekçiMurat Çaylı

Abstract

It has been demonstrated that the neutrophil/lymphocyte ratio (NLR) might be a useful marker to predict cardiovascular risk and events. We aimed to investigate the role of the NLR to predict ventricular remodeling (VR) in patients with anterior ST-elevation myocardial infarction (STEMI) who were treated with primary percutaneous coronary intervention. We prospectively included 274 consecutive anterior STEMI patients. Echocardiography was performed during admission and at six months after myocardial infarction. VR was defined as at least 20% increase from baseline in left ventricular end-diastolic volume. Patients were divided into two groups according to their VR status: VR (n=67) and non-VR (n=207). Total and differential leukocyte count, N-terminal pro-brain natriuretic peptide (NT-proBNP) and other biochemical markers were measured at admission and 24 hours later. Compared with the non-VR group, peak creatine kinase MB (CK-MB), NT-proBNP (24 h), neutrophil/lymphocyte ratio, presence of diabetes, no-reflow frequency and wall motion score index were significantly higher in patients with VR (p<0.05 for all). On multivariate logistic regression analysis, NLR (β=2.000, 95% confidence interval=1.577-2.537, p<0.001) as well as peak...Continue Reading

References

Jan 31, 1997·International Journal of Cardiology·S R Maxwell, G Y Lip
Apr 17, 1997·The New England Journal of Medicine·G OlivettiP Anversa
Jun 1, 1997·Journal of Leukocyte Biology·H Jaeschke, C W Smith
Feb 17, 1999·Journal of Molecular and Cellular Cardiology·N G FrangogiannisM L Entman
Dec 18, 2001·Cardiovascular Research·Nikolaos G FrangogiannisMark L Entman
Dec 18, 2001·Cardiovascular Research·Hans Peter HermannPaul M L Janssen
Feb 22, 2003·Journal of the American Society of Nephrology : JASN·Didier DuclouxJean-Marc Chalopin
Aug 2, 2003·Lancet·James A de LemosMark H Drazner
May 17, 2005·Journal of the American College of Cardiology·Benjamin D HorneUNKNOWN Intermountain Heart Collaborative Study Group
Jun 20, 2006·American Heart Journal·Daniel StaubChristian Mueller
Sep 9, 2008·The American Journal of Cardiology·Umesh U TamhaneHitinder S Gurm
Nov 23, 2011·Proceedings of the National Academy of Sciences of the United States of America·Eleonora MezzaromaAntonio Abbate
Jun 8, 2013·Circulation Research·Matthias Nahrendorf, Filip K Swirski
Sep 28, 2013·Journal of Cardiovascular Pharmacology·Nikolaos G Frangogiannis
Feb 18, 2014·Journal of the American College of Cardiology·Ignacio M SeropianAntonio Abbate
Mar 20, 2014·Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır·Aslı TanındıHasan Fehmi Töre

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Citations

Apr 7, 2017·Korean Circulation Journal·Süleyman ÖZzbïçer, Zekiye Melek Uluçam
Aug 30, 2018·Angiology·Lucas Rampazzo DinizKeila Lima de Oliveira Diniz
Feb 15, 2017·Current Atherosclerosis Reports·Fabrizio MontecuccoFederico Carbone
Sep 18, 2021·Journal of the American Heart Association·Gaetano TanzilliEnrico Mangieri

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Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

SPSS

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