New actigraph for long-term tremor recording

Movement Disorders : Official Journal of the Movement Disorder Society
E J Van SomerenD F Swaab

Abstract

A new method of movement analysis is validated, allowing an actigraph to discriminate tremor from other movements and store duration and intensity measures of both movement types. For algorithm optimization, wrist acceleration was recorded in nine controls and nine Parkinson's disease patients, while simultaneously rating their observed tremor minute by minute on item 20 of the Unified Parkinson's Disease Rating Scale. An optimization procedure to minimize false positives in controls while maximizing tremor detection in patients resulted in false positive tremor classification in 2.4% +/- 2.5% of the movement time of control subjects (range, 0%-7%), while providing tremor classification in 82.1% +/- 15.4% of the movement time in patients (range, 55%-100%), correlating r = 0.93 with their averaged observed tremor score. A second, generalizability study showed that application of the optimized algorithm resulted in accurate classification of 71% +/- 14% of the observed tremor time (range, 46%-90%) in another 9 patients and in a false positive classification in only 0.5% +/- 0.8% of the time in another 10 controls (range, 0%-2.4%). The commercial availability of this actigraph now for the first time makes it possible to investigat...Continue Reading

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Citations

Nov 6, 2010·Medical & Biological Engineering & Computing·Ji-Won KimKun-Woo Park
Feb 10, 2009·Proceedings of the National Academy of Sciences of the United States of America·Kun HuFrank A J L Scheer
Nov 15, 2011·Brain : a Journal of Neurology·Isabel PareésMark J Edwards
May 2, 2013·Sleep·Bart H W te Lindert, Eus J W Van Someren
Mar 5, 2010·The International Journal of Neuroscience·Santiago Perez LloretMarcelo Merello
May 17, 2011·Parkinsonism & Related Disorders·Dustin A HeldmanJoseph P Giuffrida
Mar 23, 2010·Clinical Neurology and Neurosurgery·Sharon L NaismithSimon J G Lewis
Mar 8, 2008·Journal of the Neurological Sciences·Pedro J Garcia Ruiz, Vicenta Sanchez Bernardos
Sep 11, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Susan H Fox, Anthony E Lang
Aug 25, 2007·Journal of Sleep Research·Eus J W VAN Someren
May 13, 2010·IEEE Transactions on Bio-medical Engineering·Daphne G M ZwartjesPeter H Veltink
Sep 13, 2014·Behavioural Neurology·Weidong PanYoshiharu Yamamoto
Oct 16, 2013·Parkinsonism & Related Disorders·C L PulliamD A Heldman
Jun 12, 2013·Physiology & Behavior·Weidong PanDingfang Cai
Jun 9, 2016·Movement Disorders : Official Journal of the Movement Disorder Society·Dietrich HaubenbergerRodger J Elble
Nov 21, 2007·Sleep Medicine Reviews·Eus J W Van Someren, Rixt F Riemersma-Van Der Lek
Apr 28, 2018·Movement Disorders : Official Journal of the Movement Disorder Society·Florian LipsmeierMichael Lindemann
May 1, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Weidong PanShin Kwak
Jan 12, 2022·Seminars in Neurology·Anoopum S Gupta

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