New advances in amblyopia therapy I: binocular therapies and pharmacologic augmentation

The British Journal of Ophthalmology
Courtney L Kraus, Susan M Culican

Abstract

Amblyopia therapy options have traditionally been limited to penalisation of the non-amblyopic eye with either patching or pharmaceutical penalisation. Solid evidence, mostly from the Pediatric Eye Disease Investigator Group, has validated both number of hours a day of patching and days per week of atropine use. The use of glasses alone has also been established as a good first-line therapy for both anisometropic and strabismic amblyopia. Unfortunately, visual acuity equalisation or even improvement is not always attainable with these methods. Additionally, non-compliance with prescribed therapies contributes to treatment failures, with data supporting difficulty adhering to full treatment sessions. Interest in alternative therapies for amblyopia treatment has long been a topic of interest among researchers and clinicians alike. Incorporating new technology with an understanding of the biological basis of amblyopia has led to enthusiasm for binocular treatment of amblyopia. Early work on perceptual learning as well as more recent enthusiasm for iPad-based dichoptic training have each generated interesting and promising data for vision improvement in amblyopes. Use of pharmaceutical augmentation of traditional therapies has also...Continue Reading

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Citations

Aug 23, 2019·Indian Journal of Ophthalmology·Santhan K S GopalAbhishek Pandit
Apr 9, 2019·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Sheela E KumaranKonrad Pesudovs
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Dec 16, 2020·Journal of Clinical Medicine·Carlos J Hernández-RodríguezMaría Begoña Coco-Martín
Mar 4, 2021·Seminars in Ophthalmology·Michelle M FalconeEric D Gaier
Apr 1, 2021·Expert Opinion on Drug Delivery·Ines García Del Valle, Carmen Alvarez-Lorenzo

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