New and Successful Technique for the Management of Parry-Romberg Syndrome's Soft Tissue Atrophy

The Journal of Craniofacial Surgery
Viviana Gómez Ortega, Daniel Sastoque

Abstract

Parry-Romberg syndrome (PRS) is an infrequent, acquired disorder characterized by progressive hemiatrophy of the skin and soft tissue of the face and, in some patients, results in atrophy of muscles, cartilage, and the underlying bony structures.The disease process exhibits varying speeds of development, with onset occurring in early infancy or adolescence. Clinicians have classically reserved treatment until the end of the process. Various treatment modalities have been attempted with differing results. Described treatments include free tissue transfer (omentum, rectus, latissimus, serratus, diep, scapula, and parascapular), pedicled flaps, autologous tissue (dermis-fat, bone and cartilage, and fat), and biomaterials (silicone, polyethylene, and Alloderm).In this article, the authors present a patient of Parry-Romberg syndrome in a young boy who had undergone a free flap previously, which failed to fill the atrophy of the right hemifacial soft tissues. The authors used Integra, which is a bilayer porous matrix of cross-linked bovine tendon collagen and glycosaminoglycan, and a semipermeable polysiloxane (silicone layer) and fat grafts enriched with Harvest PRP, to produce volume and symmetric contour on the affected side. The ...Continue Reading

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Citations

May 13, 2017·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Wei-Liang ChenRui Chen
May 16, 2017·The Journal of Laryngology and Otology·A HuiM Bezuhly
Jan 28, 2020·Plastic and Reconstructive Surgery·Jacqueline S IsraelJohn W Siebert
Jan 25, 2020·The Journal of Craniofacial Surgery·Guang-Can ChenYun-Bo Hao
May 26, 2021·The Journal of Prosthetic Dentistry·Rongguang LiuYuka I Sumita

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Methods Mentioned

BETA
biopsy

Software Mentioned

Integra

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