PMID: 591459Nov 1, 1977

New antitumor antibiotics, OS-4742 A1, A2, B1 and B2 produced by a strain of Streptomyces

The Journal of Antibiotics
S OmuraK Tanaka

Abstract

New antibiotics, OS-4742 A1, A2, B1 and B2, were isolated from the culture broth of the strain OS-4742, which was designated as Streptomyces matensis subsp. vineus. These compounds have anthracycline chromophores and sugar moieties, but do not contain nitrogen. They possess antimicrobial activities against Gram-positive bacteria and antitumor activities against S-180 solid tumor on mice.

Citations

Jul 15, 2009·Marine Drugs·Carlos OlanoJosé A Salas
May 28, 2010·Organic & Biomolecular Chemistry·Shunichi KusumiKazunobu Toshima
Mar 17, 2012·Angewandte Chemie·Christian M Gampe, Erick M Carreira
Jan 18, 2014·Journal of Drug Targeting·Nivesh K MittalGeorge C Wood
Feb 16, 2019·Organic & Biomolecular Chemistry·Padam P AcharyaJianglong Zhu
Feb 16, 2020·Communications Biology·Kerri A BallWilliam M Old
Sep 26, 2020·Frontiers in Microbiology·Learn-Han LeeKok-Gan Chan
Nov 29, 2005·Natural Product Reports·Tsion BililignJon S Thorson
Oct 9, 2014·Organic & Biomolecular Chemistry·Hiromasa IkedaKazunobu Toshima
Nov 20, 2016·Chemistry : a European Journal·Shunichi KusumiKazunobu Toshima
Jun 20, 2013·Chemical Communications : Chem Comm·Qian ChenGeorge A O'Doherty

Related Concepts

Antibiotics
Antibiotics, Cytotoxic
Sarcoma 180
Streptomyces

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