New approach for immobilization of 3-aminopropyltrimethoxysilane and TiO2 nanoparticles into cellulose for BJ1 skin cells proliferation

Carbohydrate Polymers
Naglaa Salem El-SayedSamir Kamel

Abstract

In the present study, tosylcellulose (TC) was used as a key intermediate for the selective coupling with 3-aminopropyltrimethoxysilane (APTMS) affording amino-propylsilane-grafted tosylcellulose (TC-Si). Solid state 13C NMR and FT-IR analyses confirmed the coupling and self-condensation of APTMS along TC. The changes in the surface morphology of the functionalized cellulose were identified by SEM imaging. The thermal stability of TC-Si was significantly improved as compared to MCC and TC. A new organic/inorganic hybrid cellulosic material was fabricated by embedding TiO2 nanoparticles into TC-Si network. The new cellulose polymers were investigated for their ability to promote the proliferation of human skin fibroblast (BJ1). The cell cytotoxicity assay showed that both TC and TC-Si possessed moderate toxicity to BJ1 cells by 17% and 23.8%, respectively at 20 μM. Meanwhile, TC-Si/TiO2 hybrid enhanced the proliferation of BJ1 by 42%. Additionally TC-Si/TiO2 hybrid demonstrated promising antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans.

References

May 24, 2005·Journal of Colloid and Interface Science·Marie-Christine Brochier SalonAlessandro Gandini
Apr 15, 2006·Toxicological Sciences : an Official Journal of the Society of Toxicology·Christie M SayesVicki L Colvin
Jul 21, 2006·The Journal of Physical Chemistry. B·Guifen FuChhiu-Tsu Lin
Feb 12, 2008·International Journal of Food Microbiology·Chamorn Chawengkijwanich, Yasuyoshi Hayata
Feb 16, 2010·Acta Biomaterialia·Daniel Arcos, María Vallet-Regí
Mar 11, 2011·Biomacromolecules·S Van VlierbergheE Schacht
Mar 24, 2012·Chemical Society Reviews·Piaoping YangJun Lin
Jun 19, 2012·Acta Biomaterialia·Ana Marina FerreiraGianluca Ciardelli
Mar 26, 2013·International Journal of Pharmaceutics·Mingqi WangHongchen Gu
Mar 29, 2013·Journal of Colloid and Interface Science·Alexandra SnyderLia Stanciu
Apr 2, 2013·ACS Applied Materials & Interfaces·Fateme RezaeiChristopher W Jones
Apr 3, 2013·Carbohydrate Polymers·Georgios ToskasThomas Hanke
Jul 6, 2014·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·A N KadamK M Garadkar
Jun 29, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Nasrin Shadjou, Mohammad Hasanzadeh
Jul 8, 2015·International Journal of Molecular Sciences·Derek H RosenzweigLisbet Haglund
Mar 16, 2016·International Journal of Biological Macromolecules·Naglaa S El-SayedRakesh K Tiwari
Feb 9, 2017·International Journal of Biological Macromolecules·Sudhanshu Shekhar BeheraAbhishek Kumar Singh
May 1, 2017·International Journal of Biological Macromolecules·Wei WangXiaoya Liu
Sep 1, 2017·International Journal of Biological Macromolecules·Hossein KhanjanzadehThomas Griesser
Oct 21, 2017·Carbohydrate Polymers·Wei ShaoXiufeng Liu
Mar 29, 2018·International Journal of Biological Macromolecules·Naglaa Salem El-SayedSamir Kamel

❮ Previous
Next ❯

Citations

May 30, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Arianna LuciaThomas Rosenau
Mar 7, 2021·Journal of Controlled Release : Official Journal of the Controlled Release Society·Parinaz AbdollahiyanAhad Mokhtarzadeh

❮ Previous
Next ❯

Related Concepts

Related Feeds

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.