New Approaches to the Immunotherapy of Type 1 Diabetes Mellitus Using Interleukin-27

Advanced Pharmaceutical Bulletin
Fatemeh ZamaniMohammad Reza Aliparasti

Abstract

Type 1 diabetes (T1D) is a pancreatic beta cell specific autoimmune disease. One of the most significant current discussions in T1D studies is therapy. Since the conventional therapy, islet transplantation and external insulin, e.g., cannot prevent the destructive autoimmune process against original beta cells and persistent hyperglycemia remains, so recent developments in the field of T1D therapy paved the way to a renewed interest in immunotherapy based on the disease process, especially monoclonal antibody therapy. Due to encouraging laboratory results, cytokine antibody-based drugs could be effective in the clinical direction of the T1D disease process. Hence, implementation of this approach can be useful to improve clinical and laboratory manifestations of T1D.

References

Nov 25, 2003·Current Opinion in Immunology·Deepak Yadav, Nora Sarvetnick
Jan 27, 2004·The Journal of Pathology·Frédérique LarousserieOdile Devergne
Oct 7, 2004·The Journal of Clinical Investigation·Kristina I Rother, David M Harlan
Mar 8, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Christoph HölscherStefan Ehlers
Aug 23, 2006·Nature Immunology·John Colgan, Paul Rothman
Jan 16, 2007·Annual Review of Medicine·Theresa T Pizarro, Fabio Cominelli
Jan 18, 2007·The Journal of Experimental Medicine·Jianguo LiuXiaojing Ma
Aug 3, 2007·Proceedings of the National Academy of Sciences of the United States of America·Maria KoulmandaTerry B Strom
Oct 22, 2008·Cellular and Molecular Life Sciences : CMLS·R WangY Li
Oct 23, 2008·Current Opinion in Immunology·Terry B Strom, Maria Koulmanda
Dec 30, 2008·Advances in Immunology·R Tisch, B Wang
Jan 24, 2009·Immunological Reviews·Katrina K HoyerAbul K Abbas
Oct 27, 2009·Current Opinion in Immunology·Maria Bettini, Dario A A Vignali
Mar 20, 2010·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Astrid C FrankTomozumi Imamichi
Apr 16, 2010·Diabetes Research and Clinical Practice·Vinicius Silva CostaMaria Elizabeth Rossi da Silva
Jul 16, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Emily Gwyer FindlayKevin N Couper
Jan 21, 2011·Physiological Reviews·Tom L van BelleMatthias G von Herrath
Mar 23, 2011·Brain, Behavior, and Immunity·Cheryl M SweeneyJean M Fletcher
Aug 20, 2011·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Bhagirath SinghAnthony M Jevnikar
Sep 29, 2011·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Kamal D Moudgil, Divaker Choubey
Nov 11, 2011·Clinical Science·Mohan R DasuRoslyn R Isseroff
Nov 24, 2011·European Journal of Human Genetics : EJHG·Katerina StechovaZdenek Sumnik
Dec 20, 2011·Trends in Immunology·Elia D Tait Wojno, Christopher A Hunter
May 23, 2012·Advances in Immunology·Aisling O'Hara HallChristopher A Hunter
Nov 6, 2012·Cold Spring Harbor Perspectives in Medicine·Mark A Atkinson
Feb 21, 2013·Diabetes·Jasmin LebastchiKevan C Herold
Apr 23, 2014·Advanced Pharmaceutical Bulletin·Venu Gopal JonnalagaddaNilakash Annaji Selkar

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