New aspects on the preparation of [11C]acetate--a simple and fast approach via distillation

Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine
Markus MitterhauserKurt Kletter

Abstract

[11C]Acetate, initially developed for nuclear cardiology has gained increased interest also for oncological problems. A conjoint problem of all preparation methods is the high sensitivity of the Grignard-precursor to moisture, demanding long cleaning and drying procedures of apparatus and reaction vials. Our rationale was to simplify and accelerate the preparation of [11C]acetate by the development of an inert, sterile and disposable system. The present publication deals with the remote-controlled preparation of [11C]acetate via distillation into a buffer ready to use.

References

Oct 31, 2002·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·D RoedaC Crouzel

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Citations

Dec 17, 2011·Nuclear Medicine and Biology·Filippo LodiStefano Boschi
Feb 26, 2010·European Journal of Radiology·W Wadsak, M Mitterhauser
Sep 7, 2006·Liver International : Official Journal of the International Association for the Study of the Liver·Shuren LiKurt Kletter
Jun 30, 2006·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Dmitri Soloviev, Claire Tamburella
Aug 27, 2013·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Xiaolan TangDahong Nie
Apr 26, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Stefan WachterKurt Kletter
Oct 1, 2010·Nuclear Medicine Communications·Chiara FeliciniPiero Alberto Salvadori
Sep 23, 2014·Nuclear Medicine Communications·Hwa Youn JangJung-Joon Min
Apr 13, 2018·Abdominal Radiology·Marzieh NejabatAlexander R Haug

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