New clinical and seasonal evidence of infections by Human Parainfluenzavirus.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
Marta E Álvarez-ArgüellesSantiago Melón García

Abstract

Human Parainfluenzaviruses (PIVs) account for a significant proportion of viral acute respiratory infections (ARIs) in children, and are also associated with morbidity and mortality in adults, including nosocomial infections. This work aims to describe PIV genotypes and their clinical and epidemiological distribution. Between December 2016 and December 2017, 6121 samples were collected, and submitted to viral culture and genomic quantification, specifically Parainfluenza 1-4 (PIV1-4), Influenza A and B, Respiratory Syncytial Virus (RSV) A and B, Adenovirus, Metapneumovirus, Coronavirus, Rhinovirus, and Enterovirus. Normalized viral load, as (log10) copies/103 cells, was calculated as virus Ct, determined by multiple qRT-PCR, as a function of the Ct of β-globin. PIV was confirmed in 268 cases (4.37%), and linked to both upper and lower respiratory tract disease, being more frequent in children than in adults (5.23 and 2.43%, respectively). PIV1 and PIV3 were most common (31 and 32.5%, of total PIV positive samples, respectively), with distribution being similar in children and adults, as was viral load. PIV type was correlated with seasonality: PIV3 being more frequent in winter and spring, PIV1 in summer, and PIV 4 in fall. No ...Continue Reading

References

May 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E WhimbeyG P Bodey
Jun 23, 2001·The New England Journal of Medicine·C B Hall
Sep 20, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Alicia M FryLarry J Anderson
Oct 7, 2008·Journal of Cardiothoracic and Vascular Anesthesia·Harry J McFarlaneWilliam F Carman
Nov 30, 2013·Influenza and Other Respiratory Viruses·Manuel V VillaranEric S Halsey
Apr 30, 2015·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Rogério PecchiniAna Catebelota
Jul 15, 2015·The New England Journal of Medicine·Seema JainUNKNOWN CDC EPIC Study Team
Feb 26, 2016·Journal of the Pediatric Infectious Diseases Society·Glen R AbediEileen Schneider
Jun 8, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Elliott Russell, Michael G Ison

❮ Previous
Next ❯

Citations

Jul 19, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Leigh M HowardCarlos G Grijalva
Aug 23, 2020·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Cheng-Chun TaiYu-Jiun Chan

❮ Previous
Next ❯

Methods Mentioned

BETA
reverse transcription PCR

Related Concepts

Related Feeds

Allergy & Infectious Diseases (ASM)

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Acute viral rhinopharyngitis

Acute viral rhinopharyngitis, also known as "common cold", is an acute, self-limiting viral infection of the upper respiratory tract involving the nose, sinuses, pharynx and larynx. Discover the latest research on acute viral rhinopharyngitis here.

Allergy & Infectious Diseases

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Related Papers

The Pediatric Infectious Disease Journal
Cristina CalvoInmaculada Casas
The Pediatric Infectious Disease Journal
Ashok SrinivasanRandall T Hayden
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Elliott Russell, Michael G Ison
© 2022 Meta ULC. All rights reserved