New closure technique for large mucosal defects after endoscopic submucosal dissection of colorectal tumors (with video)

Gastrointestinal Endoscopy
Yosuke OtakeHiroyuki Ono

Abstract

Certain large colorectal tumors satisfy expanded indications for endoscopic submucosal dissection (ESD); however, the resulting large mucosal defects may contribute to complications such as delayed bleeding and perforation. Various closure devices and methods have been developed for large mucosal defects to prevent such complications. To demonstrate the feasibility of a new and simple technique for closing large mucosal defects after colorectal ESD. Pilot feasibility study. Single center. Ten patients with 10 tumors half circumferential or less in size with sufficient muscle layer exposure after ESD were selected and treated by using the closure technique between July 2009 and June 2010. Small mucosal incisions were made around the mucosal defect by the same needle-knife used during ESD. These incisions provided a better grip for conventional clips, which then facilitated lifting the surrounding mucosa across the defect without slipping, thereby making it considerably easier to reduce the size of the defect and place additional clips. Patient characteristics and tumor clinicopathologic features were assessed as well as closure completion rate, closure procedure time, and closure-related complications. All 10 tumors were success...Continue Reading

References

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Citations

Oct 29, 2013·Best Practice & Research. Clinical Gastroenterology·Carla RolandaMário Dinis-Ribeiro
Jul 19, 2014·Gastrointestinal Endoscopy·Sergey V KantsevoyPaul J Thuluvath
Apr 23, 2014·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Kengo TakimotoKiichi Matsuyama
Jan 11, 2014·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yoshitaka NawataYoshihiro Suzuki
Aug 1, 2016·Gastrointestinal Endoscopy·Toshihiro NishizawaNaohisa Yahagi
Jan 5, 2017·Scandinavian Journal of Gastroenterology·Georgios MavrogenisKatsumi Yamamoto
Feb 10, 2017·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Teppei AkimotoNaohisa Yahagi
Mar 6, 2018·Clinical Endoscopy·Keshav KukrejaShashideep Singhal
Dec 20, 2018·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Noriko NishiyamaTsutomu Masaki
May 6, 2020·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Keiichi HashiguchiSusumu Eguchi
Aug 15, 2018·Endoscopy International Open·Toshihiro NishizawaToshio Uraoka
Aug 23, 2016·World Journal of Gastroenterology : WJG·Shintaro FujiharaTsutomu Masaki
Dec 7, 2013·Expert Review of Gastroenterology & Hepatology·Nicholas Tutticci, Michael J Bourke
Apr 29, 2020·Surgical Endoscopy·Tak Lit Derek FungKam Hung Kwok
Oct 5, 2018·World Journal of Gastrointestinal Endoscopy·Mitsuru EsakiTakuji Gotoda
Mar 4, 2021·Endoscopy International Open·Silvia PecereGuido Costamagna
Jul 3, 2021·Journal of Clinical Medicine·Yoshitsugu Misumi, Kouichi Nonaka

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