PMID: 48729May 10, 1975Paper

New complement-fixation test for the human reovirus-like agent of infantile gastroenteritis. Nebraska calf diarrhea virus used as antigen

Lancet
A Z KapikianR M Chanock

Abstract

A complement-fixation (C.F.) test for the human reovirus-like agent of infantile gastroenteritis has been developed using the serologically related Nebraska calf diarrhoea virus (N.C.D.V.) as antigen. Most infants and children who shed the agent in stools and/or who demonstrated serological (C.F.) evidence of infection with a reovirus-like-particle-positive human stool-filtrate C.F. antigen also demonstrated serological evidence of infection when a concentrated N.C.D.V. preparation was employed AS C.F. antigen. The N.C.D.V., which was previously shown to be related to the human reovirus-like agent, was found to be related antigenically to the epizootic diarrhoea of infant mice (E.D.I.M.) virus also. Studies on the prevalence of C.F. antibody in sera from infants and young children revealed a pattern of rapid acquisition of antibody to both the human reovirus-like agent and the N.C.D.V. as over 80 percent of these individuals possessed antibody to each agent by 36 months of age. A strong positive association was found in the results obtained with the two antigens. The ready availability of cell-culture grown N.C.D.V., and its ability to serve as a "substitute" C.F. antigen for the human reovirus-like agent, should enable the ser...Continue Reading

References

Jan 4, 1975·Lancet·C A MorrisH Davies
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Jun 29, 1974·Lancet·J G CruickshankO F Webster
Aug 10, 1974·Lancet·M SextonB J Ruck
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Citations

Jan 1, 1977·Archives of Virology·M S McNultyJ B McFerran
Jan 1, 1978·Archives of Virology·T H Flewett, G N Woode
Jul 1, 1976·The American Journal of Digestive Diseases·C A Mebus
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Apr 1, 1983·European Journal of Clinical Microbiology·J Forster, S Pastor
Apr 1, 1984·European Journal of Clinical Microbiology·F MorinetY Pérol
Jan 1, 1980·Transactions of the Royal Society of Tropical Medicine and Hygiene·M G RowlandW C Marshall
Oct 1, 1978·The Journal of Hygiene·C R MadeleyE J Bell
Jun 10, 1976·The New England Journal of Medicine·M H MersonE J Gangarosa
Sep 1, 1982·Australian Paediatric Journal·R J Hogg, G P Davidson
May 1, 1978·Archives of Disease in Childhood·J Walker-Smith
May 1, 1979·Archives of Disease in Childhood·H M LewisH B Valman
Sep 6, 1975·British Medical Journal
Jan 1, 1979·Journal of Clinical Pathology·C R Madeley
Jan 1, 1976·Scandinavian Journal of Infectious Diseases·I Orstavik, K W Haug
Oct 1, 1976·Journal of Comparative Pathology·D R SnodgrassE W Gray
Jun 1, 1976·Journal of Dairy Science·C A Mebus
Jan 1, 1979·Journal of Medical Virology·H K SarkkinenP E Halonen
Sep 10, 2004·Pediatric Annals·H Fred Clark, Paul A Offit
Aug 1, 1976·Acta Pathologica Et Microbiologica Scandinavica. Section B, Microbiology·B Tufvesson, T Johnsson
Jan 24, 1976·The Medical Journal of Australia·M B Albrey, A M Murphy
Jan 1, 1977·Journal of Clinical Microbiology·S MatsunoR Kono
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Nov 1, 1979·Infection and Immunity·D Y Graham, M K Estes
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Dec 1, 1977·Applied and Environmental Microbiology·R L Ward, C S Ashley
Jun 1, 1984·Microbiological Reviews·G Cukor, N R Blacklow
Sep 1, 1978·Journal of Clinical Microbiology·R H YolkenR M Chanock

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