New Danish reference values for spirometry

The Clinical Respiratory Journal
Anders LøkkeP Lange

Abstract

International recommendations state that reference values for lung function should derive from cross-sectional studies of healthy nonsmokers and be renewed from time to time because of cohort effect and newer, more accurate, technical equipment. In 1986, the Danish Lung Society published reference values for spirometry based on 570 individuals aged 30-70 years. To produce new reference values for lung function and to extend the existing values by including individuals between 20 and 30 years of age and older than 70 years of age. Two similar but independent studies was used: The 2001-2003 examination of the Copenhagen City Heart Study and the 2003–2010 examination of the Copenhagen General Population Study. Of a total of 69 822 individuals, we included 11 288 healthy never-smoking white individuals to produce the reference values: 6307 women and 4981 men, 20 years of age or older with adequate lung function. We used sex-stratified multiple linear regression analysis to find prediction formulas for forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC adjusted for age and height. The cutoff value of normal lung function was defined as the fifth percentile (also named the 5% quantile) according to gende...Continue Reading

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Citations

Mar 31, 2015·Clinical Physiology and Functional Imaging·A KainuA R A Sovijärvi
Jul 15, 2015·The New England Journal of Medicine·Peter LangeJørgen Vestbo
Apr 25, 2018·European Journal of Epidemiology·Gitte FærkBørge G Nordestgaard
Apr 25, 2018·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Yunus ÇolakBørge G Nordestgaard
Sep 14, 2017·Clinical Cardiology·Louis Lind PlesnerKasper Iversen
Jun 16, 2018·The European Respiratory Journal·Mathias MunkholmJann Mortensen
Mar 18, 2019·Interactive Cardiovascular and Thoracic Surgery·Emilie C RisomHanne B Ravn
Nov 27, 2019·American Journal of Respiratory and Critical Care Medicine·Yunus ÇolakPeter Lange
Apr 15, 2020·American Journal of Respiratory and Critical Care Medicine·Jacob Louis MarottPeter Lange
Jan 8, 2017·BMC Pulmonary Medicine·Morten DalsgaardKasper Iversen
Jun 30, 2019·The European Respiratory Journal·Yunus ÇolakShoaib Afzal
Feb 12, 2020·Scientific Reports·Kristoffer L NorheimPascal Madeleine
Mar 29, 2020·NPJ Primary Care Respiratory Medicine·Lene Maria ØrtsAnders Løkke
Aug 21, 2020·The European Respiratory Journal·Signe Vedel-KroghSune F Nielsen
Feb 10, 2021·International Archives of Occupational and Environmental Health·Stinna SkaabyJens Peter Ellekilde Bonde
Dec 30, 2020·BMJ Open Respiratory Research·Truls Sylvan IngebrigtsenPeter Lange
Nov 4, 2020·American Journal of Respiratory and Critical Care Medicine·Yunus ÇolakJørgen Vestbo
Jun 6, 2021·Acta Anaesthesiologica Scandinavica·Emilie C RisomHanne B Ravn
Jul 15, 2021·Respiratory Medicine·Signe Vedel-KroghJørgen Vestbo
Jul 8, 2021·American Journal of Respiratory and Critical Care Medicine·Jacob Louis MarottPeter Lange

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