New endoscopy advances to refine adenoma detection rate for colorectal cancer screening: None is the winner

World Journal of Gastrointestinal Oncology
Marcello MaidaGiuseppe Scarpulla

Abstract

Colorectal cancer (CRC) is the third most common cancer in males and second in females, and globally the fourth cause for cancer death worldwide. Oncological screening of CRC has a major role in the management of the disease and it is mostly performed by colonoscopy. Anyway, effectiveness of endoscopic screening for CRC strictly depends on adequate detection and removal of potentially precancerous lesions, and accuracy of colonoscopy in detection of adenomas is still suboptimal. For this reason, several technological advances have been implemented in order to improve the diagnostic sensitivity of colonoscopy in adenoma detection. Among these: (1) Visual technologies such as chromoendoscopy and narrow band imaging; (2) optical innovation as high definition endoscopy, full-spectrum endoscopy or Third Eye Retroscope; and (3) mechanical advances as Cap assisted colonoscopy, Endocuff, Endoring and G-Eye endoscope. All these technologies advances have been tested over time by clinical studies with mixed results. Which of them is more likely to be successful in the next future?

References

Apr 26, 2006·The American Journal of Gastroenterology·Douglas K RexUNKNOWN ASGE/ACG Taskforce on Quality in Endoscopy
Jun 15, 2006·The American Journal of Gastroenterology·Dorte Ejg JarbolOve B Schaffalitzky de Muckadell
May 14, 2010·The New England Journal of Medicine·Michal F KaminskiEugeniusz Butruk
Nov 12, 2010·Gastrointestinal Endoscopy·Anke M LeufkensUNKNOWN Third Eye Retroscope Randomized Clinical Evaluation [TERRACE] Study Group
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Apr 22, 2017·Gastroenterology·Michal F KaminskiJaroslaw Regula

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