New findings useful for clinical practice using swept-source optical coherence tomography angiography in the follow-up of active ocular toxoplasmosis

International Journal of Retina and Vitreous
João Rafael de Oliveira DiasRubens Belfort

Abstract

Ocular toxoplasmosis is one of the most common causes of intraocular inflammation and posterior uveitis in immunocompetent patients. This paper aims to investigate swept-source optical coherence tomography angiography (SS-OCTA) findings in eyes with active toxoplasmic retinochoroiditis. This case series was conducted from November 2017 through October 2019 in two Brazilian centers. 15 eyes of 15 patients with active toxoplasmic retinochoroiditis were included, and were imaged at baseline and after at least 4 weeks of follow-up. All patients underwent ophthalmic examinations and multimodal imaging including SS-OCT and SS-OCTA before and after treatment of ocular toxoplasmosis. The differential diagnoses included toxoplasmosis, syphilis, and human immunodeficiency virus, which were eliminated through serologic and clinical evaluations. All 15 patients presented with positive anti-Toxoplasma gondii immunoglobulin G titers and three also presented with positive anti-T. gondii immunoglobulin M titers. The mean age at examination was 32.4 years ± 12.7 years (range 15-59 years). Sixty percent of the patients were female. In all eyes, the inner retinal layers were abnormally hyperreflective with full-thickness disorganization of the re...Continue Reading

References

Feb 1, 1977·American Journal of Ophthalmology·H D Perry, R L Font
Aug 15, 1992·American Journal of Ophthalmology·P D GlasnerR Belfort Júnior
Dec 1, 1996·The British Journal of Ophthalmology·C E Pavesio, S Lightman
Jun 15, 2004·Lancet·J G Montoya, O Liesenfeld
Aug 6, 2004·Japanese Journal of Ophthalmology·Leyla S AtmacaFigen Batioglu
Nov 14, 2006·Parasite Immunology·L A JonesC W Roberts
Jun 21, 2008·Investigative Ophthalmology & Visual Science·Jeff FinglerScott E Fraser
Mar 28, 2009·Experimental Parasitology·J L Jones, J P Dubey
Sep 3, 2011·Journal of Global Infectious Diseases·João M FurtadoKevin L Winthrop
Mar 14, 2012·Investigative Ophthalmology & Visual Science·Reza MotaghiannezamScott E Fraser
Sep 14, 2012·Acta Ophthalmologica·Juliana L OréficeUNKNOWN Grupo Mineiro de Pesquisa em Doenças Oculares Inflamatórias (MINAS)
Apr 10, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Dafna GoldenbergZohar Habot-Wilner
Jul 5, 2013·Bulletin of the World Health Organization·Paul R Torgerson, Pierpaolo Mastroiacovo
Sep 17, 2013·The Korean Journal of Parasitology·Young-Hoon Park, Ho-Woo Nam
Feb 11, 2014·Ophthalmology·Karen B SchaalMichael Engelbert
Sep 10, 2014·Journal of Ophthalmology·Meredith Harrell, Petros E Carvounis
Sep 30, 2014·European Journal of Ophthalmology·Álvaro RodríguezFrancisco Rodríguez
Jan 1, 2013·Retinal Cases & Brief Reports·Ahmad A AlwassiaCaroline R Baumal
Jul 18, 2015·Journal of Ophthalmic Inflammation and Infection·Sharat HegdeHarry W Flynn
May 4, 2017·Progress in Retinal and Eye Research·Francesco PichiSunil K Srivastava
Jun 15, 2017·Ophthalmic Surgery, Lasers & Imaging Retina·Fatih Mehmet TürkcüÜmit Karaalp
Sep 14, 2018·Journal of Ophthalmic Inflammation and Infection·Aniruddha AgarwalVishali Gupta
May 18, 2019·Ophthalmic Surgery, Lasers & Imaging Retina·Nicolas A YannuzziK Bailey Freund
May 30, 2019·Journal of Ophthalmic Inflammation and Infection·Vita L S DingerkusMatthias Becker
Sep 13, 2019·Progress in Retinal and Eye Research·Francesco PichiMarion R Munk

❮ Previous
Next ❯

Citations

Jan 30, 2021·Asia-Pacific Journal of Ophthalmology·Padmamalini MahendradasRamesh Venkatesh
Aug 10, 2021·International Ophthalmology·Dimitrios KalogeropoulosChris Kalogeropoulos

❮ Previous
Next ❯

Methods Mentioned

BETA
imaging technique

Software Mentioned

OCT
SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.