New genes in inflammatory bowel disease: lessons for complex diseases?

Lancet
Daniel R GayaJack Satsangi

Abstract

The chronic inflammatory bowel diseases Crohn's disease and ulcerative colitis are common causes of gastrointestinal disease in northern Europe, affecting as many as one in 250 people. Although mortality is low, morbidity associated with these diseases is substantial. We review the recent advances in the genetics of inflammatory bowel disease, with particular emphasis on the data that have been generated since the discovery of the CARD15 (NOD2) gene in 2001.

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Citations

Jan 9, 2007·Inflammatory Bowel Diseases·Johan Van LimbergenJack Satsangi
Sep 11, 2007·Inflammatory Bowel Diseases·Alfonso MartínezElena Urcelay
Dec 20, 2007·Inflammatory Bowel Diseases·Laura StronatiSalvatore Cucchiara
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Apr 9, 2008·Inflammatory Bowel Diseases·Bertus EksteenDavid H Adams
Jul 16, 2008·Inflammatory Bowel Diseases·Pieta TurunenKaija-Leena Kolho
Sep 26, 2008·Inflammatory Bowel Diseases·Claudio Fiocchi
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