New Hope in Prostate Cancer Precision Medicine? miRNA Replacement and Epigenetics

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
Anders Bjartell

Abstract

SPINK1+/ETS- prostate cancer is an aggressive disease with poor clinical outcome. New data suggest a novel treatment by upregulating the expression of miR-338-5p/-421 through epigenetic modulation or by miRNA replacement. This is a new and interesting concept that warrants further exploration in clinical trials.See related article by Bhatia et al., p. 2755.

References

Jun 10, 2008·Cancer Cell·Scott A TomlinsArul M Chinnaiyan
Mar 4, 2011·Science Translational Medicine·Bushra AteeqArul M Chinnaiyan
Dec 28, 2018·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Vipul BhatiaBushra Ateeq

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Citations

Jul 30, 2019·Trends in Molecular Medicine·Vipul Bhatia, Bushra Ateeq
Sep 21, 2021·European Journal of Histochemistry : EJH·Wanchun WangZhangren Yan

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