New horizon for high performance Mg-based biomaterial with uniform degradation behavior: Formation of stacking faults

Scientific Reports
Jinghuai ZhangRuizhi Wu

Abstract

Designing the new microstructure is an effective way to accelerate the biomedical application of magnesium (Mg) alloys. In this study, a novel Mg-8Er-1Zn alloy with profuse nano-spaced basal plane stacking faults (SFs) was prepared by combined processes of direct-chill semi-continuous casting, heat-treatment and hot-extrusion. The formation of SFs made the alloy possess outstanding comprehensive performance as the biodegradable implant material. The ultimate tensile strength (UTS: 318 MPa), tensile yield strength (TYS: 207 MPa) and elongation (21%) of the alloy with SFs were superior to those of most reported degradable Mg-based alloys. This new alloy showed acceptable biotoxicity and degradation rate (0.34 mm/year), and the latter could be further slowed down through optimizing the microstructure. Most amazing of all, the uniquely uniform in vitro/vivo corrosion behavior was obtained due to the formation of SFs. Accordingly we proposed an original corrosion mechanism for the novel Mg alloy with SFs. The present study opens a new horizon for developing new Mg-based biomaterials with highly desirable performances.

References

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Citations

Aug 5, 2017·Materials·Karthika PrasadKateryna Bazaka
Dec 23, 2017·International Journal of Molecular Sciences·Ke YangXingdong Zhang
Jun 6, 2019·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Xiaobo ZhangYujuan Wu
Mar 11, 2019·ACS Biomaterials Science & Engineering·Hongwei MiaoGuangyin Yuan

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Methods Mentioned

BETA
electron diffraction
scanning
X-ray
electron

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