New hydrophilic interaction/reversed-phase mixed-mode stationary phase and its application for analysis of nonionic ethoxylated surfactants

Journal of Chromatography. a
Xiaodong Liu, Christopher Pohl

Abstract

We have developed a new stationary phase that combines both hydrophilic interaction and reversed-phase characteristics. The new phase is based on high-purity, porous and spherical silica gel functionalized with a silyl ligand consisting of both hydrophilic and hydrophobic functionalities. This phase can be operated in both HILIC mode (high organic solvent) and RPLC mode (low organic solvent). An optimal balance of hydrophilic and hydrophobic moieties on the silica surface provides unique chromatographic properties that make it useful for determination of alkyl chain distribution and degree of ethoxylation (EO number) of nonionic ethoxylated surfactants.

References

Jul 29, 1994·Journal of Chromatography. a·A J AlpertR Orlando
Jul 20, 2000·Journal of Chromatography. B, Biomedical Sciences and Applications·P DalletJ P Dubost
Sep 12, 2001·The Journal of Biological Chemistry·I Schmitt, L Gerace
Mar 5, 2003·Journal of Chromatography. a·Hiroyuki TanakaOhira Masayoshi
Sep 15, 2006·Journal of Separation Science·Petrus Hemström, Knut Irgum

❮ Previous
Next ❯

Citations

Apr 5, 2011·Analytical and Bioanalytical Chemistry·Shazia Abrar, Bernd Trathnigg
Feb 16, 2010·Journal of Separation Science·Anna Micó-TormosGuillermo Ramis-Ramos
Mar 12, 2010·Journal of Separation Science·Mohammed E A IbrahimCharles A Lucy
Dec 6, 2017·Journal of Separation Science·Dan LiuZhi-Guo Shi
Mar 31, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Evelin FarsangKrisztián Horváth
Feb 23, 2020·Analytical and Bioanalytical Chemistry·Daniel ZahnThomas P Knepper
Sep 30, 2018·Analytical and Bioanalytical Chemistry·Ludivine FereyKaren Gaudin
Aug 13, 2013·Journal of Chromatography. a·Andrea F G GarganoMichael Lämmerhofer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.