New Imaging Tracers for the Infected Diabetic Foot (Nuclear and Optical Imaging)

Current Pharmaceutical Design
Alfred O AnkrahPhilip H Elsinga

Abstract

Diabetic Foot Infections (DFIs) are associated with increased morbidity, an economic burden on patients, their families and healthcare systems and increased mortality. Early diagnosis with prompt, appropriate and adequate treatment of the infected diabetic foot is crucial. The determination of DFIs, however, may be quite perplexing and invasive. Imaging is useful in the evaluation of certain cases of DFIs, especially in suspected instances with no overt clinical features, or in the diagnosis of osteomyelitis. Nuclear medicine imaging is currently used in the evaluation of DFIs; however, like all the imaging techniques now available, it has its limitations. Several radiopharmaceuticals presently available play useful roles in the management of DFIs, while new ones are being evaluated. Optical imaging techniques have recently demonstrated promising results in the evaluation of many infections including DFIs. Using the same molecule, a tracer can be labeled with a radioisotope or an optical imaging dye. This enables infections to be evaluated both pre- and intra-operatively when surgery is required in their management. In some cases, tracers have been simultaneously labeled with both a radioisotope and an optical imaging dye to pr...Continue Reading

Citations

Mar 17, 2020·Diabetes/metabolism Research and Reviews·Éric SennevilleEdgar J G Peters
Jun 3, 2021·Journal of Fungi·Alfred O AnkrahAndor W J M Glaudemans

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antiparasitics

Antiparasitics are medications which are indicated for the treatment of parasitic diseases. Discover the latest research on antiparasitics here.

Related Papers

The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutica
Sherif Heiba, Karin Knešaurek
Nuclear Medicine Communications
Gabriela CapriottiAlberto Signore
Baillière's Best Practice & Research. Clinical Rheumatology
J S Tan, T M File
© 2022 Meta ULC. All rights reserved