New imidazole alkaloids and zinc complexes from the micronesian sponge Leucetta cf. chagosensis

Journal of Natural Products
Xiong FuM Kelly-Borges

Abstract

Four new imidazole alkaloids, 2-5, along with the known isonaamidine B (1) were isolated from a Pacific sponge, Leucetta cf. chagosensis, collected from Yap, Federated States of Micronesia. Among these, 4 and 5 are zinc complexes derived from isonaamidine B and isonaamidine D. The structures of the new compounds were elucidated from spectral data. Isonaamidine D (3) showed weakly antifungal activity against Aspergillus niger with MIC = 100 micrograms/mL.

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Citations

Apr 26, 2012·Organic Letters·Heather M LimaCarl J Lovely
Sep 13, 2012·Organic Letters·Joseph B GibbonsRyan E Looper
Sep 4, 2015·Natural Products and Bioprospecting·Hao WenYongsheng Che
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Jan 29, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Kai-Kai GongGuo-Qiang Li
Oct 29, 2010·Natural Product Reports·Panduka B Koswatta, Carl J Lovely
Jun 5, 2012·Natural Product Reports·Mélanie RouéMarie-Lise Bourguet-Kondracki
Dec 13, 2019·Journal of Asian Natural Products Research·Jian-Hong GanHao-Bing Yu
Nov 13, 2018·Journal of Asian Natural Products Research·Wei-Zhuo TangHou-Wen Lin
Jul 29, 2008·The Journal of Organic Chemistry·Denis S Ermolat'ev, Erik V Van der Eycken
Apr 13, 2018·Journal of Natural Products·Wei-Zhuo TangHou-Wen Lin
Jan 27, 2006·Organic Letters·Nicholas S AberleKeith G Watson

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