PMID: 30020573Jul 19, 2018Paper

New indications for existing drugs; repurposing in psychiatry and addiction medicine

Nederlands tijdschrift voor geneeskunde
Jurriaan F M Strous, Wim van den Brink

Abstract

Repurposing is the discovery - whether or not by accident - of a new use for an existing product, for example, a new indication for a drug. In the past, several psychotropic drugs have received their place in the treatment arsenal via this route. Both in psychiatry and addiction medicine, there is an important need for new treatments with new working mechanisms. Potential new uses in both psychiatry and addiction medicine of several drugs that have already been registered for other indications are currently under study. For example, the anaesthetic ketamine is found to have a strong antidepressant effect. In addition, both the anti-epileptic topiramate and the muscle-relaxant baclofen could possibly prevent relapse in addictive behaviours.

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