New insecticides with ecdysteroidal and juvenile hormone activity

Annual Review of Entomology
T S DhadiallaD P Le

Abstract

Agrochemical research over the last two decades has resulted in the discovery of chemically novel insecticides that mimic the action of the two insect growth and developmental hormones, the steroidal 20-hydroxyecdysone (20E) and the sesquiterpenoid juvenile hormone (JH). Bisacylhydrazines are non-steroidal agonists of 20E and exhibit their insecticidal activity via interaction with the ecdysteroid receptor proteins. Interestingly, two of the bisacylhydrazine (tebufenozide and RH-2485) insecticides are very selectively toxic to lepidopteran pests. These insecticides are safe to beneficial insects and have a benign ecotoxicological profile. Aromatic non-terpenoidal insecticides (fenoxycarb and pyriproxyfen) mimic the action of JHs. However, like the JHs, their exact mode of action is not well understood. These insecticides are toxic to a broad spectrum of insects during their embryonic, last larval, or reproductive stages. The insecticidal, ecotoxicological properties and the mode of action of the two groups of insecticides are reviewed in this article.

References

Jan 1, 1975·Annual Review of Entomology·G B Staal
Jan 1, 1991·Archives of Insect Biochemistry and Physiology·M Spindler-BarthK D Spindler
Sep 1, 1990·Journal of Medical Entomology·A A MarchiondoJ H Slusser
Nov 1, 1986·Developmental Biology·T G Wilson, J Fabian
Jan 1, 1974·Cold Spring Harbor Symposia on Quantitative Biology·M AshburnerG Richards
Jun 1, 1994·Ecotoxicology and Environmental Safety·D P KreutzweiserD C Eichenberg
Nov 1, 1995·Circulation·S V LichtensteinS E Fremes
Jun 20, 1995·Proceedings of the National Academy of Sciences of the United States of America·M A HarmonD J Mangelsdorf
Jun 1, 1995·Insect Biochemistry and Molecular Biology·F Engelmann
Jul 1, 1995·Insect Biochemistry and Molecular Biology·H FujiwaraL M Riddiford
Jan 1, 1995·Insect Biochemistry and Molecular Biology·W L ChoA S Raikhel
Jul 1, 1994·Science·H F Nijhout
May 6, 1994·Journal of Molecular Biology·G TzertzinisF C Kafatos
Dec 15, 1995·Cell·D J MangelsdorfR M Evans
Jan 1, 1996·Archives of Insect Biochemistry and Physiology·L M Riddiford
Jun 1, 1996·Insect Biochemistry and Molecular Biology·A ElbrechtR Borris

❮ Previous
Next ❯

Citations

Oct 12, 2010·Analytical and Bioanalytical Chemistry·Arti T NavareFacundo M Fernández
Dec 29, 2006·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Christina M Grozinger, Gene E Robinson
Jun 2, 2007·Molecular Biology Reports·Dantong YangXiaofan Zhao
Feb 7, 2007·Transgenic Research·Lauralynn KourtzKristi D Snell
Nov 20, 2012·Environmental Science and Pollution Research International·Koffi T Tassou, Ralf Schulz
May 26, 2004·Ecotoxicology and Environmental Safety·Oliver LichtRoland Nagel
Nov 6, 2003·Insect Biochemistry and Molecular Biology·Luc Swevers, Kostas Iatrou
Jun 28, 2005·Insect Biochemistry and Molecular Biology·Stéphanie Auzoux-BordenaveStéphane Debernard
Nov 20, 2003·Journal of Insect Physiology·David C HaywardVirginia K Walker
May 29, 2003·Journal of Insect Physiology·Nancy E. BeckageFrances F. Tan
May 29, 2003·Journal of Insect Physiology·M M. Adel, F Sehnal
Jun 8, 2001·Phytochemistry·L Dinan
Apr 23, 2003·Ecotoxicology and Environmental Safety·A E BayoumiD Ordóñez
Oct 25, 2003·Ecotoxicology and Environmental Safety·Gema P DavisonOlga Sonia León
Aug 4, 1999·Molecular and Cellular Endocrinology·S C PereraS R Palli
Jan 5, 2002·Insect Biochemistry and Molecular Biology·Yoshiaki NakagawaTamio Ueno
Jan 5, 2002·Insect Biochemistry and Molecular Biology·M SundaramA Retnakaran
Dec 3, 2002·Insect Biochemistry and Molecular Biology·Chieka MinakuchiManabu Kamimura
Oct 2, 1998·Insect Biochemistry and Molecular Biology·M SundaramA Retnakaran
Oct 21, 1999·Insect Biochemistry and Molecular Biology·M VögtliV C Henrich
Apr 2, 2003·Current Opinion in Plant Biology·Malla Padidam
Aug 21, 2003·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Faïza TaïbiNadia Soltani-Mazouni
Oct 1, 2009·Integrative and Comparative Biology·Robert J DenverJohn C Wingfield
Jan 1, 2008·Acta Crystallographica. Section E, Structure Reports Online·Xi-Chen LiYun Ling
Jan 1, 2009·Acta Crystallographica. Section E, Structure Reports Online·Xiao HuRunling Wang
Jan 1, 2009·Acta Crystallographica. Section E, Structure Reports Online·Shi-Jie ZhangWei-Xiao Hu
Dec 6, 2011·Acta Crystallographica. Section F, Structural Biology and Crystallization Communications·Kang Wei TanYu Keung Mok

❮ Previous
Next ❯

Methods Mentioned

BETA
in vitro transcription
scanning electron microscopy

Software Mentioned

ROMDAN
MIMIC
CONFIRM
INSEGAR

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.