PMID: 16632100DOI: 10.1016/j.ecl.2006.02.014Apr 25, 2006Paper
New insights in the molecular pathogenesis of the maternally inherited diabetes and deafness syndrome
Endocrinology and Metabolism Clinics of North America
J A MaassenLeen M 'T Hart
Abstract
The 3243A>G mutation in mitochondrial DNA (mtDNA) is a genetic variant that is associated with a high risk of developing diabetes during life. Enhanced aging of pancreatic beta-cells, a reduced capacity of these cells to synthesize large amounts of insulin,and a resetting of the ATP/ADP-regulated K-channel seem to be the pathogenic factors involved.
References
Aug 1, 1992·Nature Genetics·J M van den OuwelandJ A Maassen
Apr 1, 1992·Nature Genetics·S W BallingerD C Wallace
Jan 1, 1992·Journal of Inherited Metabolic Disease·D C WallaceM D Brown
Dec 13, 1990·Nature·Y GotoS Horai
Oct 27, 1989·Science·M P King, G Attardi
Apr 9, 1981·Nature·S AndersonI G Young
Jun 1, 1994·Journal of Bioenergetics and Biomembranes·M D Brown, D C Wallace
Nov 1, 1993·The Journal of Clinical Investigation·F MatschinskyT L Jetton
Apr 1, 1993·Acta Pathologica Japonica·S HamazakiT Sugiyama
Apr 1, 1996·Diabetes·G VelhoP Froguel
Jan 1, 1997·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M P van de CorputA K Raap
Oct 6, 1997·Diabetes·T KobayashiK Kosaka
Aug 26, 1998·Biochimica Et Biophysica Acta·G Lenaz
Mar 5, 1999·Science·D C Wallace
Apr 2, 1999·Diabetes·L M t HartR J Heine
Apr 6, 1999·Proceedings. Biological Sciences·E HagelbergD K Bowden
May 7, 1999·Diabetologia·J M van den OuwelandJ A Maassen
Jul 30, 1999·Nature Medicine·M BriniR Rizzuto
Oct 9, 1999·The Journal of Biological Chemistry·G M JanssenJ M van Den Ouweland
Feb 15, 2001·Nature Genetics·K P Steel, C J Kros
Mar 10, 2001·Recent Progress in Hormone Research·M RodenG I Shulman
May 1, 2001·Annals of Internal Medicine·P J GuillausseauB Vialettes
Nov 19, 2002·Diabetologia·A H Khan, J E Pessin
Nov 19, 2002·Diabetologia·T NomiyamaS Ohta
Mar 11, 2003·Diabetologia·S LynnD M Turnbull
Oct 1, 2003·Human Mutation·Anna L Gloyn
Jan 30, 2004·Diabetes·J Antonie MaassenHerman H P J Lemkes
Mar 20, 2004·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·C E M De BlockJ-J Martin
Apr 30, 2004·The New England Journal of Medicine·Anna L GloynAndrew T Hattersley
May 28, 2004·Nature·Aleksandra TrifunovicNils-Göran Larsson
Jun 30, 2004·Diabetes & Metabolism·P J GuillausseauUNKNOWN GEDIAM, Mitochondrial Diabetes French Study Group
Jul 28, 2004·Diabetes·Antonio L Cuesta-MuñozMarkku Laakso
Mar 23, 2005·Current Opinion in Cell Biology·D Grahame Hardie
May 28, 2005·Diabetes·Leen M 't HartJ Antonie Maassen
Jul 16, 2005·Annals of Medicine·Johannes A MaassenLeen M 't Hart
Jul 16, 2005·Science·G C KujothT A Prolla
Oct 6, 2005·Mutation Research·Roshan S Jahangir TafrechiAnton K Raap
❮ Previous
Next ❯
Citations
Oct 13, 2009·Journal of Inherited Metabolic Disease·M SchiffP Rustin
Apr 17, 2008·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Julie Robitaille, Althea M Grant
Oct 19, 2010·Journal of Diabetes Investigation·Soo Heon KwakHong Kyu Lee
Oct 13, 2011·BMC Medical Genetics·Hideki MutaiTatsuo Matsunaga
Apr 26, 2008·Endocrine Reviews·Lydia Aguilar-Bryan, Joseph Bryan
Oct 29, 2009·Endocrine Reviews·Ines Pagel-LangenickelMichael N Sack
Feb 17, 2010·Endocrine Reviews·Mary-Elizabeth Patti, Silvia Corvera
Apr 27, 2012·PloS One·Cristina MazzaccaraLucia Sacchetti
Apr 22, 2014·Journal of Diabetes and Its Complications·Aye NaingGul Bano
Dec 30, 2015·Heart Failure Reviews·Ying-Han R HsuGavin Y Oudit
Dec 14, 2011·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Elena GarcíaFederico Hawkins
Aug 2, 2008·Clinics in Geriatric Medicine·John E Morley
Jan 27, 2009·Arquivos brasileiros de endocrinologia e metabologia·Daisy CrispimLuis H Canani
Apr 23, 2009·Chinese Medical Sciences Journal = Chung-kuo I Hsüeh K'o Hsüeh Tsa Chih·Shi ZhangHeng Wang
Oct 5, 2006·The Journal of Clinical Endocrinology and Metabolism·Lois E Donovan, Naomi E Severin
Oct 21, 2006·Biochemical Society Transactions·J A MaassenH H Lemkes
Oct 18, 2007·Current Opinion in Endocrinology, Diabetes, and Obesity
❮ Previous
Next ❯
Related Concepts
Related Feeds
Auditory Perception
Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.
Related Papers
Diabetes
J A MaassenHerman H P J Lemkes
The Journal of Laryngology and Otology
T HowesV Das
Diabetic Medicine : a Journal of the British Diabetic Association
R MurphyAndrew T Hattersley
Diabetes/metabolism Research and Reviews
Nóra HosszúfalusiPál Pánczél
Nature Genetics
J M van den OuwelandJ A Maassen