New insights into food protein-induced enterocolitis in children.

Minerva pediatrica
Carla MastrorilliCarlo Caffarelli

Abstract

Food protein-induced enterocolitis syndrome (FPIES) represents a non-IgE-mediated food allergic disorder with delayed gastrointestinal symptoms that may evolve in a medical emergency. Clinically, FPIES can be distinguished into acute and chronic phenotypes. FPIES is mainly diagnosed in infancy however the onset at older ages is being progressively described. The pathogenetic mechanism underlying FPIES remains mainly unexplained, but an alteration of food-specific T-cell response has been proposed. The diagnosis of FPIES is primarily clinical, since there are not available specific biomarkers. Oral food challenge (OFC) is the gold standard for diagnosing FPIES or excluding the onset of tolerance to the triggering food. Management of FPIES includes an acute phase treatment and a maintenance therapy with the strict food avoidance until challenge, in order to prevent new attacks and avoid nutritional alterations. Acute management requires hydration that can be performed orally or intravenously according to clinical status. Long-term management of FPIES is based on the avoidance of the culprit food(s) and supervised introduction of other high-risk foods if never taken before among infants before 12 months of age. There is a compelli...Continue Reading

References

May 1, 1989·Digestive Diseases and Sciences·G K PowellR M Goldblum
Oct 1, 1996·The Journal of Allergy and Clinical Immunology·N BenlounesM Heyman
Mar 1, 1997·The Journal of Allergy and Clinical Immunology·K M HoffmanH A Sampson
Aug 26, 1998·The Journal of Pediatrics·S H SichererH A Sampson
Dec 24, 2005·Allergologia et immunopathologia·L Zapatero RemónM I Martínez Molero
Oct 3, 2008·Archives of Disease in Childhood·J-B HwangA S Kim
Feb 4, 2009·Pediatrics·Sam MehrAndrew S Kemp
Dec 28, 2010·Journal of the American Dietetic Association·Joshua A BoyceMatthew J Fenton
May 21, 2011·Expert Review of Clinical Immunology·Jean-Christoph Caubet, Anna Nowak-Węgrzyn
Oct 23, 2012·The Journal of Allergy and Clinical Immunology·Hideaki MoritaKenji Matsumoto
Nov 13, 2012·Allergologia et immunopathologia·S Miceli SopoM Calvani
Jul 24, 2013·Proceedings of the National Academy of Sciences of the United States of America·Arnold HanMark M Davis
Jul 31, 2013·The Journal of Allergy and Clinical Immunology·Teri HolbrookRobert A Wood
Jan 10, 2014·Allergy, Asthma & Immunology Research·Omer F BeşerFügen Ç Cokuğraş
Feb 26, 2014·The Journal of Allergy and Clinical Immunology. in Practice·Melanie A RuffnerJonathan M Spergel
Mar 7, 2014·Clinical and Translational Allergy·Laura Merras-SalmioErkki Savilahti
Apr 2, 2014·Current Opinion in Allergy and Clinical Immunology·Sam MehrDianne E Campbell
May 24, 2014·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·George V GuibasKostas N Priftis
Jun 2, 2014·The Journal of Allergy and Clinical Immunology·Jean Christoph CaubetAnna Nowak-Węgrzyn
Jul 6, 2014·International Archives of Allergy and Immunology·Stefano Miceli SopoSerena Monaco
May 10, 2015·The Journal of Allergy and Clinical Immunology·Anna Nowak-WęgrzynSibylle Koletzko
Aug 20, 2015·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Stefano Miceli SopoGiovanna Monti
Nov 21, 2015·The Journal of Allergy and Clinical Immunology·Giampaolo Ricci, Carlo Caffarelli
Jan 30, 2016·Pediatrics International : Official Journal of the Japan Pediatric Society·Mitsuaki KimuraShiro Seto
Aug 11, 2016·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Stefano Miceli SopoSerena Monaco
Aug 23, 2016·The Journal of Allergy and Clinical Immunology·Jean Christoph CaubetAnna Nowak-Węgrzyn
Jan 7, 2017·Allergology International : Official Journal of the Japanese Society of Allergology·Mitsuaki KimuraShiro Seto
Feb 14, 2017·The Journal of Allergy and Clinical Immunology·Ritobrata GoswamiM Cecilia Berin
Feb 18, 2017·Journal of Investigational Allergology & Clinical Immunology·A Nowak-WęgrzynApb Moschione Castro
Apr 5, 2017·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Valentina PecoraAlessandro Fiocchi
Apr 22, 2017·The Journal of Allergy and Clinical Immunology·Sam MehrUNKNOWN FPIES Study Group
Jul 20, 2017·Journal of Asthma and Allergy·Marine MicheletJean-Christoph Caubet
Nov 9, 2017·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Carla MastrorilliKarin Hoffmann-Sommergruber
Feb 15, 2018·The World Allergy Organization Journal·Stephanie A LeonardAnna Nowak-Wegrzyn
Feb 15, 2018·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Simona BarniElio Novembre
May 15, 2018·The Journal of Clinical Investigation·Louise F RisnesLudvig M Sollid
Aug 4, 2018·Journal of Investigational Allergology & Clinical Immunology·S Khan
Sep 24, 2018·The Journal of Allergy and Clinical Immunology. in Practice·Kathleen Y WangTerri F Brown-Whitehorn
Sep 24, 2018·The Journal of Allergy and Clinical Immunology·Sara Bellón AlonsoLuis Ángel Echeverría Zudaire
Nov 21, 2018·Nutrients·Carlo CaffarelliGiampaolo Ricci
Dec 13, 2018·Journal of Pediatric Gastroenterology and Nutrition·Claudio RomanoCarmelo Scarpignato

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Citations

Aug 1, 2020·Minerva pediatrica·Riccardo CastagnoliGian Luigi Marseglia

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