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New insights on single-stranded versus double-stranded DNA library preparation for ancient DNA

BioTechniques

Dec 15, 2015

Nathan WalesM Thomas P Gilbert

Abstract

An innovative single-stranded DNA (ssDNA) library preparation method has sparked great interest among ancient DNA (aDNA) researchers, especially after reports of endogenous DNA content increases >20-fold in some samples. To investigate the behavior of this method, we generated ssDNA and...read more

Mentioned in this Paper

AdnA protein, Pseudomonas fluorescens
Research Personnel
Ancient DNA
Sequence Determinations, DNA
probe gene fragment
cDNA Library
Nucleic Acid Strand
DNA
Bowel Preparation
DNA, Single-Stranded
1
79
1
Paper Details
References
  • References12
  • Citations6
12
  • References12
  • Citations6
1

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New insights on single-stranded versus double-stranded DNA library preparation for ancient DNA

BioTechniques

Dec 15, 2015

Nathan WalesM Thomas P Gilbert

PMID: 26651516

DOI: 10.2144/000114364

Abstract

An innovative single-stranded DNA (ssDNA) library preparation method has sparked great interest among ancient DNA (aDNA) researchers, especially after reports of endogenous DNA content increases >20-fold in some samples. To investigate the behavior of this method, we generated ssDNA and...read more

Mentioned in this Paper

AdnA protein, Pseudomonas fluorescens
Research Personnel
Ancient DNA
Sequence Determinations, DNA
probe gene fragment
cDNA Library
Nucleic Acid Strand
DNA
Bowel Preparation
DNA, Single-Stranded
1
79
1

Similar Papers Found In These Feeds

Ancient DNA

Ancient DNA sequences are able to offer valuable insights into molecular evolutionary processes, but are notoriously difficult to analyze due to molecular damage and exogenous dna contamination. Discover the latest research on Ancient DNA here.

Related Papers

Public Health Nursing

An historic time

Public Health NursingJanuary 7, 2014
Patricia J Kelly
Paper Details
References
  • References12
  • Citations6
12
  • References12
  • Citations6
1
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