New introduction and spread of rabies among dog population in Bangui

Acta Tropica
E NakounéAlain Le Faou

Abstract

Rabies is endemic in the Central African Republic (CAR) and a neglected enzootic disease which represents a serious public health problem. Before April 2009, rabies was not a notifiable disease in CAR. Vaccination of animals is expensive and not commonly done. In 2005, none rabies case was recorded in Bangui. To understand how rabies was introduced and propagated in the city of Bangui from 2006 to 2008, we analyzed samplings of dog brain as well as reviewed the records of dog owners. A total of 86 out of 101 samples (84.8%) tested positive for rabies virus during this period. Previous phylogenetic analysis of some strains circulating in Bangui between 2006 and 2008 indicated that virus of cosmopolitan and Africa 2 clade are found. Given the time frame and location of these samples, one possible explanation for this alarming result may be that two different strains of rabies virus were introduced at different times in Bangui. Stray dogs are solely responsible for the spread of the epidemic.

References

May 9, 2002·Emerging Infectious Diseases·Marc-Alain WiddowsonJames McGrane
Sep 28, 2005·The Journal of General Virology·H BourhyP J Walker
Apr 25, 2007·Proceedings of the National Academy of Sciences of the United States of America·Katie HampsonAndy Dobson
Feb 9, 2008·Emerging Infectious Diseases·Cheryl CohenLucille Blumberg
Oct 22, 2008·The Journal of General Virology·Hervé BourhyEdward C Holmes
Nov 26, 2008·PLoS Neglected Tropical Diseases·Katie HampsonSarah Cleaveland

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Citations

Jun 27, 2015·PLoS Neglected Tropical Diseases·Salome Dürr, Michael P Ward
Feb 10, 2016·PLoS Neglected Tropical Diseases·Vianney TricouMirdad Kazanji
Jun 16, 2016·PloS One·Li-Peng SongQiong Shi
May 27, 2020·PLoS Neglected Tropical Diseases·Davide ColombiVittoria Colizza
May 15, 2020·Acta Tropica·Céline MbiloJakob Zinsstag

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