New invasive patterns as a prognostic factor for superficial esophageal cancer.

Journal of Gastroenterology
E ItoH Makuuchi

Abstract

Prognostic factors for superficial esophageal cancer cannot be limited to such factors as lymph node metastasis (N factor), depth of tumor invasion (T factor), and genetic alterations. The purpose of this study was to examine whether invasive growth patterns of tumors, such as infiltrative growth pattern c (INFc) and budding, represent new useful prognostic factors for superficial esophageal cancer. We investigated 87 cases of superficial esophageal cancer in patients treated with radical surgery. First, the invasive growth pattern of the tumor was pathologically evaluated based on the traditional infiltrative growth pattern (INF) classification. Next, new INF criteria were proposed, and the invasive pattern was re-evaluated. We also investigated budding (Bud) in the stroma of the invasive frontal lesion. When the patients were divided into two groups, with and without an INFc component, the group with an INFc component had a poorer outcome than the group without an INFc component. When the group with an INFc component was defined as "new INFc", new INFc was correlated with the T factor (p = 0.006) and the ly factor (lymphatic invasion) (p = 0.041). Bud was correlated with the T factor (p = 0.001), the N factor (p = 0.030), and...Continue Reading

References

Jan 1, 1991·Cancer Investigation·L A LiottaP S Steeg
Feb 1, 1986·Journal of Surgical Oncology·K SugimachiK Jingu
Jan 15, 2000·Annals of Surgery·H UenoT Yamamoto
Sep 20, 2001·International Journal of Molecular Medicine·O ChinoH Makuuchi
Jul 9, 2004·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Shoji NatsugoeTakashi Aikou
Aug 10, 2004·Gastroenterology·Hideki UenoShinya Bekku
Dec 1, 2004·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·M S RohP J Choi
Jan 6, 2007·Histopathology·F Prall
Dec 3, 2009·Gastrointestinal Endoscopy Clinics of North America·Haruhiro InoueShin-ei Kudo

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Citations

Nov 10, 2013·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Lang YangXiu-wu Bian
Jun 23, 2015·Molecular Medicine Reports·Makiko TanakaSadaki Inokuchi
Jul 18, 2015·Histopathology·Alhadi AlmangushIlmo Leivo
Oct 25, 2013·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·R DhuparW L Hofstetter
Nov 24, 2018·Journal of Clinical Pathology·Bochao ZhaoBaojun Huang
Mar 6, 2017·Molecular Medicine Reports·Ryota MasudaMasayuki Iwazaki
Sep 10, 2020·Nature Reviews. Clinical Oncology·Alessandro LugliIris D Nagtegaal
Mar 23, 2018·Digestive Diseases and Sciences·T MizumotoK Chayama
Jan 26, 2020·Virchows Archiv : an International Journal of Pathology·Valeria MaffeisAmbrogio Fassina
Jul 1, 2020·British Journal of Cancer·Inti ZlobecAlessandro Lugli
Feb 18, 2017·Bulletin of Mathematical Biology·Lu PengMark A J Chaplain
Jul 18, 2020·BMJ Open Gastroenterology·Maelle AnciauxCaroline Vandeputte
May 26, 2020·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Sivesh K KamarajahEwen A Griffiths
Mar 31, 2021·Journal of Theoretical Biology·Linnea C FranssenMark A J Chaplain

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