New ion exchange materials for use in a 82Sr/82Rb generator

Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine
P SylvesterA Cisar

Abstract

82Rb is a short-lived positron-emitting isotope (T1/2 = 75 s) that is increasingly being used in positron emission tomography for the evaluation of myocardial perfusion. The short half-life of 82Rb results in rapid decay of the administered radioactivity allowing repeat scans to be performed after a relatively short time interval. The 82Rb is available from a 82Sr/82Rb generator in which the 82Sr parent is immobilized on an ion exchange column and 82Rb eluted when required. Consequently, suitable ion exchangers for use in a generator must have a very high affinity for strontium and a negligible affinity for rubidium, allowing the pure 82Rb to be safely and efficiently eluted in high yields. This study evaluated a number of strontium-selective ion exchange materials using batch experiments and identified sodium nonatitanate as the best material for use in a 82Sr/82Rb generator.

Citations

Dec 5, 2012·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·N P van der MeulenH G Raubenheimer
Feb 3, 2009·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·S DharaP Chattopadhyay
Dec 20, 2005·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·P SylvesterT W Adams
Dec 3, 2014·Journal of Hazardous Materials·Arnaud VillardJean-François Dufrêche

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