PMID: 7543484Aug 15, 1995Paper

New knowledge in primary biliary cirrhosis

Hospital Practice
M Eric Gershwin, I R Mackay

Abstract

The autoantibodies characteristic of the disease react against mitochondrial enzymes essential to the function of all body cells, yet the disease is highly focused on only one tissue: the epithelial lining of intrahepatic bile ductules. The explanation may lie in tissue-specific cell-surface expression of a triggering antigen.

References

Mar 1, 1991·Gastroenterology·M E Gershwin, I R Mackay
Sep 1, 1989·Immunology Today·I R Mackay, M E Gershwin
Feb 26, 1987·The New England Journal of Medicine·M M Kaplan
Dec 1, 1950·Medicine·E H AHRENSS H BLONDHEIM

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Citations

Jul 1, 1998·The American Journal of Gastroenterology·T H ZukowskiK D Lindor
May 16, 2000·The American Journal of Gastroenterology·W R KimK D Lindor

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