New marine natural products from sponges (Porifera) of the order Dictyoceratida (2001 to 2012); a promising source for drug discovery, exploration and future prospects

Biotechnology Advances
Mohammad Ferdous MehbubChristopher Franco

Abstract

The discovery of new drugs can no longer rely primarily on terrestrial resources, as they have been heavily exploited for over a century. During the last few decades marine sources, particularly sponges, have proven to be a most promising source of new natural products for drug discovery. This review considers the order Dictyoceratida in the Phylum Porifera from which the largest number of new marine natural products have been reported over the period 2001-2012. This paper examines all the sponges from the order Dictyoceratida that were reported as new compounds during the time period in a comprehensive manner. The distinctive physical characteristics and the geographical distribution of the different families are presented. The wide structural diversity of the compounds produced and the variety of biological activities they exhibited is highlighted. As a representative of sponges, insights into this order and avenues for future effective natural product discovery are presented. The research institutions associated with the various studies are also highlighted with the aim of facilitating collaborative relationships, as well as to acknowledge the major international contributors to the discovery of novel sponge metabolites. The...Continue Reading

Citations

Oct 3, 2017·Annual Review of Pharmacology and Toxicology·Asmaa Boufridi, Ronald J Quinn
Feb 8, 2020·Chemistry : a European Journal·Ömer TaspinarHans-Günther Schmalz
May 18, 2020·Marine Drugs·Oh-Seok KwonJongheon Shin
Mar 11, 2017·Pharmaceutical Biology·Aleksandra TalevskaSlavisa Stankovic
Apr 25, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Abdulrahman M AlahdalSameh S Elhady
May 8, 2018·Natural Product Research·Camilla Silva de FigueiredoJosean Fechine Tavares
May 10, 2019·Current Microbiology·Gyana Prakash MahapatraJayanta Kumar Patra
Jul 24, 2018·Frontiers in Microbiology·Akram NajafiIraj Nabipour
Oct 9, 2019·Scientific Reports·Diana H QuanJames A Triccas
Nov 1, 2020·Archives of Microbiology·Akhitha Mary BennySanil Nandiath Karayi
Mar 8, 2019·Journal of Natural Products·Ying WuHou-Wen Lin
Aug 26, 2017·Journal of Natural Products·Masumi ToriiSachiko Tsukamoto
Sep 9, 2021·Letters in Applied Microbiology·E R AbdelaleemS Y Desoukey

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