New method of treatment for dentin hypersensitivity by precipitation of calcium phosphate in situ

Dental Materials Journal
Y Imai, T Akimoto

Abstract

The hydrodynamic theory is generally accepted as an explanation of hypersensitive dentin and suggests that occlusion of exposed dentinal tubules should result in a reduction of hypersensitivity. We tried to block tubules by in situ precipitation of insoluble calcium phosphate. Calcium phosphate crystals precipitated in situ on patent dentin surfaces and formed in the tubules immediately upon serial application of sodium phosphate and calcium chloride solutions, thus occluding the tubules. The size of crystals, their degree of coverage, and the thickness of the precipitate depended on the method of application and concentration of the solutions. The application of 5% disodium phosphate solution followed by rubbing with 10% calcium chloride solution resulted in immediate relief from dental hypersensitivity in 84% of patients treated.

Citations

Sep 13, 2015·Dental Materials : Official Publication of the Academy of Dental Materials·Deepak MehtaKeiichi Sasaki
Apr 17, 2004·Journal of Clinical Periodontology·N Banfield, M Addy
Nov 21, 2012·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Ornnicha ThanatvarakornJunji Tagami
Jun 1, 2011·Australian Dental Journal·Z DongA Joiner
Jun 10, 2014·Acta Odontologica Scandinavica·Deepak MehtaKeiichi Sasaki
Aug 2, 2013·Dental Materials Journal·Ornnicha ThanatvarakornJunji Tagami
Aug 15, 2006·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Aishuan Maria CherngLaurence Chow
May 2, 2009·Journal of Dental Research·A J GoldbergR B Kazemi
Dec 9, 2014·ACS Nano·Yu-Chih ChiangChun-Pin Lin

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