New methodologies in ageing research

Ageing Research Reviews
Brenna OsborneMorten Scheibye-Knudsen

Abstract

Ageing is arguably the most complex phenotype that occurs in humans. To understand and treat ageing as well as associated diseases, highly specialised technologies are emerging that reveal critical insight into the underlying mechanisms and provide new hope for previously untreated diseases. Herein, we describe the latest developments in cutting edge technologies applied across the field of ageing research. We cover emerging model organisms, high-throughput methodologies and machine-driven approaches. In all, this review will give you a glimpse of what will be pushing the field onwards and upwards.

References

Oct 1, 1975·British Journal of Cancer·R PetoJ Clack
Jun 1, 1969·Proceedings of the National Academy of Sciences of the United States of America·J E Cleaver
Dec 2, 1993·Nature·C KenyonR Tabtiang
Jan 15, 1998·Cell·D A Sinclair, L Guarente
Jun 6, 1998·Experimental Gerontology·D E Martínez
Nov 30, 2000·Proceedings of the National Academy of Sciences of the United States of America·S ZouY N Jan
Jan 19, 2002·Annals of the New York Academy of Sciences·T E Seeman, E Crimmins
May 15, 2002·Current Biology : CB·Scott D PletcherLinda Partridge
Jun 20, 1959·Nature·R K MORTIMER, J R JOHNSTON
Nov 7, 2003·Science of Aging Knowledge Environment : SAGE KE·Rochelle Buffenstein, Jennifer U M Jarvis
Nov 18, 2003·Annual Review of Genetics·Stephen L Helfand, Blanka Rogina
Dec 31, 2003·Experimental Gerontology·Thomas E Johnson
Aug 13, 2004·Proceedings. Biological Sciences·Margaret E HallPat Monaghan
Sep 9, 2004·Science·David KiplingRichard G A Faragher
Apr 28, 2005·Current Biology : CB·Martial Depczynski, David R Bellwood
Sep 6, 2005·Mechanisms of Ageing and Development·Miguel CoronaGene E Robinson
May 5, 2006·Human Mutation·Shurong HuangJunko Oshima
Jun 23, 2006·Archives of Disease in Childhood·T O CrawfordH M Lederman
Feb 8, 2008·The New England Journal of Medicine·Melissa A MeridethWendy J Introne
May 20, 2008·Free Radical Research·Doris AbeleEva E R Philipp
Jun 13, 2008·Biotechnology Journal·Stefano SalvioliClaudio Franceschi
Mar 24, 2009·Cell Cycle·Christopher R BurtnerMatt Kaeberlein
Mar 25, 2009·Proceedings of the National Academy of Sciences of the United States of America·E Brendan RoarkDavid A Mucciarone
Jul 10, 2009·Nature·David E HarrisonRichard A Miller
Oct 9, 2009·The New England Journal of Medicine·Jan H J Hoeijmakers
Jan 15, 2010·NeuroImage·Katja FrankeUNKNOWN Alzheimer's Disease Neuroimaging Initiative
Mar 24, 2010·Proceedings of the National Academy of Sciences of the United States of America·Vincent Julien LecomteHenri Weimerskirch
Apr 14, 2010·FEBS Letters·Daniel Münch, Gro V Amdam
Jun 11, 2010·Proceedings of the National Academy of Sciences of the United States of America·David K WoodBevin P Engelward
Jan 6, 2011·JAMA : the Journal of the American Medical Association·Stephanie StudenskiJack Guralnik
Jul 7, 2011·Neuropsychology·Frank R LinSusan M Resnick
Jul 7, 2011·PloS One·Sven BocklandtEric Vilain
Mar 17, 2012·Proceedings of the National Academy of Sciences of the United States of America·Sung Sik LeeMatthias Heinemann
Apr 5, 2012·The Journal of Experimental Medicine·Morten Scheibye-KnudsenVilhelm A Bohr
May 3, 2012·Nature Reviews. Genetics·Peter B JensenSøren Brunak
May 26, 2012·Experimental Gerontology·Nicholas BakerGro V Amdam
Nov 28, 2012·Molecular Cell·Gregory HannumKang Zhang
Dec 12, 2012·Frontiers in Genetics·Paola Sebastiani, Thomas T Perls

❮ Previous
Next ❯

Citations

Dec 31, 2020·Aging·Garik V MkrtchyanMorten Scheibye-Knudsen
Aug 4, 2021·Aging and Disease·Fedor GalkinAlex Zhavoronkov

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved