New methodology to obtain a calibration model for noninvasive near-infrared blood glucose monitoring

Applied Spectroscopy
Katsuhiko MaruoYukio Yamada

Abstract

This paper reports new methodology to obtain a calibration model for noninvasive blood glucose monitoring using diffuse reflectance near-infrared (NIR) spectroscopy. Conventional studies of noninvasive blood glucose monitoring with NIR spectroscopy use a calibration model developed by in vivo experimental data sets. In order to create a calibration model, we have used a numerical simulation of light propagation in skin tissue to obtain simulated NIR diffuse reflectance spectra. The numerical simulation method enables us to design parameters affecting the prediction of blood glucose levels and their variation ranges for a data set to create a calibration model using multivariate analysis without any in vivo experiments in advance. By designing the parameters and their variation ranges appropriately, we can prevent a calibration model from chance temporal correlations that are often observed in conventional studies using NIR spectroscopy. The calibration model (regression coefficient vector) obtained by the numerical simulation has a characteristic positive peak at the wavelength around 1600 nm. This characteristic feature of the regression coefficient vector is very similar to those obtained by our previous in vitro and in vivo ...Continue Reading

References

May 8, 2001·The Journal of Nutrition·G L Coté
Jan 31, 2002·Journal of Biomedical Optics·Ralf Marbach
Sep 5, 2003·Physics in Medicine and Biology·Masatoshi TarumiYukio Yamada
Oct 14, 2004·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Ping Du YiYukihiro Ozaki
Aug 27, 2005·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Yi Ping DuYukihiro Ozaki
Sep 1, 2005·Analytical Chemistry·Mark A Arnold, Gary W Small

❮ Previous
Next ❯

Citations

Apr 14, 2007·Analytical and Bioanalytical Chemistry·Venkata Radhakrishna Kondepati, H Michael Heise
Jun 26, 2012·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Yukihiro Ozaki
Apr 26, 2007·Applied Spectroscopy·Yusuf Sulub, Gary W Small
Nov 3, 2007·Physics in Medicine and Biology·Elaine A Ryan, Michael J Farquharson
Jun 14, 2013·Biomedical Optics Express·Wanjie ZhangKexin Xu
Jul 30, 2014·Biomedical Optics Express·Sabbir LiakatClaire F Gmachl
Apr 20, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Nan LiYaoyong Meng
Mar 7, 2021·Biosensors·José Luis Cano PerezRoberto Rojas Laguna
May 20, 2008·Analytical Chemistry·Barry Lavine, Jerome Workman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.