New molecular diagnostic tools in traveller's diarrhea

Journal of Travel Medicine
J Vila

Abstract

Traveller's diarrhea can be caused by bacteria, protozoa, helminths and viruses. Globally, the most common causes of traveller's diarrhea are two pathotypes of Escherichia coli (enterotoxigenic and enteroaggregative) and Shigella, although there are significant variations according to the geographic area visited. While traveller's diarrhea is usually a mild, self-limiting disease, half of the travellers with traveller's diarrhea have some limitation in their activities during the journey and up to 10% present persistent diarrhea or other complications, making microbiological diagnosis necessary. The aim of this article is to describe the application of new molecular diagnostic tools mainly based on multiplex PCR, including their advantages and disadvantages as well as the current gaps that requiring further study.

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Citations

Feb 3, 2018·Journal of Travel Medicine·Bradley A ConnorOlga Whyte
Jul 18, 2018·Journal of Travel Medicine·Mark S Riddle
May 16, 2019·Recent Patents on Inflammation & Allergy Drug Discovery·Alexander K C LeungKam L Hon
May 3, 2018·Journal of Travel Medicine·Tristan P Learoyd, Rupert M Gaut
Oct 14, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mark S RiddleUNKNOWN TrEAT TD Study Team
Apr 3, 2021·Pediatrics in Review·Hiba ChehabJohn C Christenson

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