PMID: 9168593Jun 1, 1997Paper

New objective classification system for nuclear opacification

Journal of the Optical Society of America. A, Optics, Image Science, and Vision
D D DuncanO D Schein

Abstract

We have developed an autonomous objective classification scheme for degree of nuclear opacification. The algorithm was developed by using a series of color 35-mm slides acquired with a Topcon photo slit-lamp microscope and use of standard camera settings. The photographs were digitized, and first, and second-order gray-level statistics were extracted from within circular regions of the nucleus. Classifications of severity were performed by using these features as input to a neural network. Training versus classification performance was tested by using photographs of different eyes, and test/retest classification reproducibility was evaluated by using paired photographs of the same eyes. We demonstrate good performance of the classifier against subjective assessments rendered by the Wilmer grading system [Invest. Ophthalmol. Visual Sci. 29, 73 (1988)] and markedly better test/retest reproducibility.

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Citations

Feb 5, 2010·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Karl JensenBarbara E K Klein
Dec 23, 2015·Computational and Mathematical Methods in Medicine·Shu TianHong-Wei Hao
Aug 4, 2010·IEEE Transactions on Medical Imaging·Wei HuangTien Yin Wong
Feb 23, 2010·IEEE Transactions on Bio-medical Engineering·Huiqi LiTien Yin Wong
Jun 17, 2015·IEEE Transactions on Bio-medical Engineering·Xinting GaoTien Yin Wong
Jan 1, 2012·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Dilraj Singh Grewal, Satinder Pal Singh Grewal
Sep 2, 2014·BMC Medical Informatics and Decision Making·Zhuo ZhangJiang Liu
Nov 16, 2010·Journal of Internal Medicine·F Sjöqvist, Y Böttiger
Sep 19, 2018·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Abdullah M Al-Osaily, Mohanna Y Al-Jindan
Aug 25, 2020·Journal of Ophthalmology·Shenming HuWei He
Apr 1, 2014·Journal of Medical Imaging·Ruchir SrivastavaTien Yin Wong
Nov 30, 2018·Current Opinion in Ophthalmology·Helena E GaliNatalie A Afshari

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