PMID: 1194709Nov 1, 1975Paper

New observations in the histopathology of erythema nodosum

The Journal of Investigative Dermatology
R K Winkelmann, L Förström

Abstract

Erythema nodosum presents variable clinical and histologic patterns of response in the vessels, septa, and fat lobules of the subcutaneous tissue. Acute or chronic phlebitis with hemorrhage may be commonly observed; acute panniculitis is observed in foci, but at time it may be the principal histologic feature; lymphocytic infiltration of fat lobules is often found, and lymphoid nodules are not infrequent; rarely, chronic granulomatous lesions involve septa or fat lobules; and proliferative lipocyte response may be observed. Because these variable histologic patterns may be coexistent, excision biopsy and multiple sections are necessary to recognize them. The variable histologic features correlate with the different clinical forms: acute nodular, chronic nodular, migrating plaque lesion, cellulitis, and the rate suppurative form. This variety of panniculus response in erythema nodosum can be explained on the basis of host-tissue response to a delayed hypersensitivity reaction to an antigenic stimulus.

Citations

Jan 1, 1992·Scandinavian Journal of Rheumatology·J E NaschitzJ H Boss
Mar 1, 1991·The British Journal of Dermatology·I J Umbert, R K Winkelmann
Mar 1, 1987·International Journal of Dermatology·J LichtensteinE F Sherertz
Feb 1, 1993·International Journal of Dermatology·M D Sanz VicoE Sánchez Yus
Dec 1, 1996·Seminars in Cutaneous Medicine and Surgery·W L WhiteM G Hitchcock
Dec 17, 2009·Transplant Infectious Disease : an Official Journal of the Transplantation Society·O GheithM R N Nampoory
Feb 1, 1978·The British Journal of Dermatology·W M HendricksE Gratz
Oct 1, 1989·Journal of Cutaneous Pathology·S I ChunR S Rogers
Sep 1, 1993·The British Journal of Dermatology·A C AkdişB Oral
May 2, 2002·International Journal of Dermatology·Maria Clara Gutierrez GalhardoAntônio Carlos Francesconi do Valle
Jan 31, 2006·Journal of Cutaneous Pathology·Stacy Thurber, Sabine Kohler
Feb 13, 2007·Clinical Rheumatology·M Ginarte, J Toribio
Feb 21, 2007·Journal of the European Academy of Dermatology and Venereology : JEADV·N Ortego-CentenoT Caballero-Morales
Sep 21, 2007·Multiple Sclerosis : Clinical and Laboratory Research·E ThouvenotW Camu
Apr 3, 1999·Seminars in Cutaneous Medicine and Surgery·W L White, M G Hitchcock
Dec 1, 1996·Revista de saúde pública·M C PiresN Y Valente
Jun 5, 2007·Seminars in Cutaneous Medicine and Surgery·Luis Requena, Evaristo Sánchez Yus
Dec 1, 1995·International Journal of Dermatology·M A AbdallahN Kamel
Dec 1, 1995·FEMS Immunology and Medical Microbiology·C GeistK Zwingenberger
Feb 1, 1992·Seminars in Arthritis and Rheumatism·J E NaschitzJ H Boss

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