New-Onset Atrial Fibrillation in Patients With Primary Aldosteronism Receiving Different Treatment Strategies: Systematic Review and Pooled Analysis of Three Studies.

Frontiers in Endocrinology
Cheng-Hsuan TsaiYen-Hung Lin

Abstract

Primary aldosteronism (PA) is a common cause of secondary hypertension and associated with higher incidence of new-onset atrial fibrillation (NOAF). However, the effects of surgical or medical therapies on preventing NOAF in PA patents remain unclear. The aim of this meta-analysis study was to assess the risk of NOAF among PA patients receiving mineralocorticoid receptor antagonist (MRA) treatment, PA patients receiving adrenalectomy, and patients with essential hypertension. We performed the meta-analysis of the randomized or observational studies that investigated the incidence rate of NOAF in PA patients receiving MRA treatment versus PA patients receiving adrenalectomy from database inception until December 01, 2020 which were identified from PubMed, Embase, and Cochrane Library. A total of 172 related studies were reviewed, of which three fulfilled the inclusion criteria, including a total of 2,705 PA patients. The results of meta-analysis demonstrated a higher incidence of NOAF among the PA patients receiving MRA treatment compared to the PA patients receiving adrenalectomy (pooled odds ratio [OR]: 2.83, 95% confidence interval [CI]: 1.76-4.57 in the random effects model, I 2 = 0%). The pooled OR for the PA patients recei...Continue Reading

References

Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Apr 20, 2005·Journal of the American College of Cardiology·Paul MilliezJean-Jacques Mourad
May 12, 2007·Clinical Endocrinology·William F Young
Jan 16, 2008·Archives of Internal Medicine·Cristiana CatenaLeonardo A Sechi
Mar 4, 2008·Trends in Endocrinology and Metabolism : TEM·Gian-Paolo RossiJohn W Funder
Feb 5, 2009·The Journal of Clinical Endocrinology and Metabolism·E Born-FrontsbergUNKNOWN Participants of the German Conn's Registry
Feb 2, 2010·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·C CatenaL A Sechi
Aug 6, 2011·European Heart Journal·Jan-Christian ReilHans-Ruprecht Neuberger
Dec 3, 2011·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·A Hannemann, H Wallaschofski
Jun 13, 2012·Journal of Hypertension·Yen-Hung LinUNKNOWN TAIPAI Study Group
Nov 7, 2012·Circulation·Michael A Rosenberg, Warren J Manning
Sep 24, 2013·The Journal of Clinical Endocrinology and Metabolism·Paolo MulateroFranco Veglio
Jan 29, 2014·The Journal of Biological Chemistry·Daniel LavallUlrich Laufs
Aug 22, 2015·Journal of the American College of Cardiology·Mikhail S DzeshkaEduard Shantsila
Mar 5, 2016·The Journal of Clinical Endocrinology and Metabolism·John W FunderWilliam F Young
Oct 14, 2016·BMJ : British Medical Journal·Jonathan Ac SterneJulian Pt Higgins
Nov 20, 2016·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Vin-Cent WuShih-Chieh Jeff Chueh
Nov 29, 2016·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Chern-En ChiangShih-Ann Chen
Dec 23, 2016·Kardiologia polska·Paulus KirchhofPanagiotis Vardas
Jan 8, 2017·International Journal of Cardiology·J NeefsJ R de Groot
Mar 8, 2017·Hypertension·Teresa M SecciaGian Paolo Rossi
Jul 1, 2017·Journal of Hypertension·Vin-Cent WuUNKNOWN TAIPAI Study Group
Jul 25, 2017·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Vin-Cent WuUNKNOWN TAIPAI group
Nov 4, 2017·The Journal of Clinical Endocrinology and Metabolism·Marieke VelemaUNKNOWN SPARTACUS investigators
Dec 5, 2017·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·Jacques W M LendersMartin Reincke
Jan 24, 2018·Cardiovascular Research·Chia-Hung ChouUNKNOWN TAIPAI Study Group
Feb 28, 2018·Hypertension·Gian Paolo RossiUNKNOWN PAPY Study Investigators
Mar 7, 2018·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Kuo-How HuangUNKNOWN TAIPAI, Taiwan Primary Aldosteronism Investigator
Jul 11, 2018·Hypertension·Gregory L HundemerAnand Vaidya
May 31, 2019·Journal of Hypertension·Takuyuki KatabamiUNKNOWN JPAS/JRAS Study Group
Dec 24, 2019·Cardiology in Review·Padma Raghavan PillaiIrene A Weiss
Jan 9, 2020·Journal of Hypertension·Athanasios Manolis, Michael Doumas
Apr 15, 2020·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·Chien-Ting PanUNKNOWN TAIPAI Study Group
Oct 18, 2020·Journal of Human Hypertension·Cheng-Hsuan TsaiYen-Hung Lin

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Software Mentioned

RevMan
Embase
Comprehensive Meta - Analysis
ROBINS
Cochrane

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