New-onset atrial fibrillation is an independent predictor of mortality in medical intensive care unit patients

The Annals of Pharmacotherapy
Alyssa Y ChenIshaq Lat

Abstract

Atrial fibrillation (AF) has been extensively studied in postoperative critically ill surgical patients, but little literature exists to describe the outcomes of patients in the medical intensive care unit (ICU). To determine the incidence of new-onset AF in patients admitted to a medical ICU and if new-onset AF was associated with adverse clinical outcomes. This was a single-center, retrospective study of all adult patients admitted to the medical ICU at an academic medical center for >24 hours between December 2008 and April 2010. Collected data included past medical history, incidence of new-onset AF, Acute Physiology and Chronic Health Evaluation II scores, organ failure, length of stay in the ICU and hospital, and in-hospital and 60-day survival. A total of 741 patients were included. New-onset AF occurred in 53 patients (7.2%). In-hospital mortality was significantly greater for patients with new-onset AF (45% vs 16%; adjusted odds ratio [OR] = 2.21, 95% CI 1.07-4.54, P = 0.032), as was 60-day mortality (51% vs 23%; adjusted OR = 1.99, 95% CI = 1.01-3.91, P = 0.047). Patients with new-onset AF experienced greater ICU (6 ± 10.2 days vs 3 ± 3.6 days, P < 0.01) and hospital (15 ± 19 days vs 7 ± 9 days, P < 0.01) lengths of s...Continue Reading

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Citations

Sep 1, 2015·Anesthesiology Clinics·Maurice F Joyce, John Adam Reich
Nov 5, 2016·Journal of Critical Care·Perliveh CarreraTeng Moua
Aug 8, 2015·Journal of Intensive Care Medicine·Jeremiah J DubyChristine S Cocanour
Dec 19, 2017·Journal of Atrial Fibrillation·William F McIntyre, Jeff Healey
Nov 8, 2018·European Heart Journal. Acute Cardiovascular Care·William F McIntyreJeff S Healey
Oct 20, 2017·Current Opinion in Cardiology·William F McIntyreJeff S Healey
Nov 20, 2016·Critical Care : the Official Journal of the Critical Care Forum·Wen Cheng LiuWei Shiang Lin
May 16, 2019·Intensive Care Medicine·Mik WetterslevMorten Hylander Møller
Jun 16, 2018·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Giuseppe BorianiUNKNOWN ESC Scientific Document Group
May 7, 2021·BMC Cardiovascular Disorders·Jun QianLin Che
Jun 27, 2021·Pacing and Clinical Electrophysiology : PACE·Ryan BrunettiPrashant D Bhave

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