New-onset COPD and Decline in Lung Function Among Wood Dust-Exposed Workers: Re-analysis of a 6-year Follow-up Study

Annals of Work Exposures and Health
Anneli C S BolundVivi Schlünssen

Abstract

There is a lack of longitudinal studies exploring the association between organic wood dust exposure and new-onset chronic obstructive pulmonary disease (COPD) and change in lung function. We have re-investigated these associations in a 6-year follow-up cohort of furniture workers exposed to wood dust using improved outcome measures and methods. A large follow-up study of 1112 woodworkers (63%) from the Danish furniture industry and 235 controls (57%) was conducted between 1998 and 2004. Forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), and the ratio (FEV1/FVC) standardized for age, height, and sex using the Global Lung Function Initiative 2012 equations were assessed at baseline and follow-up. Questionnaires on respiratory symptoms, wood dust exposure, and smoking habits were collected. Exposure was assessed as exposure level at baseline and as cumulative exposure in the follow-up period from quantitative task specific job exposure matrix available at both baseline and follow-up based on personal dust sampling using passive dust monitors. The association between exposure to wood dust and new-onset COPD was assessed with logistic regression, whereas the association between wood dust and the longi...Continue Reading

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