New-onset of postoperative atrial fibrillation is likely to recur in the absence of other triggers

Therapeutics and Clinical Risk Management
Jesper Park-HansenHelena Dominguez

Abstract

Incident atrial fibrillation (AF) is reported in 10%-65% of patients without previous AF diagnosis after open heart surgery. The risk of late AF recurrence after a postoperative AF onset is unclear, and it is controversial whether AF limited to the postoperative period should elicit oral anticoagulation (OAC) therapy. The primary objective of this study was to evaluate the long-term recurrence of AF in patients developing new-onset peri-procedural AF. Patients (n=189) with available baseline and follow-up data included in Left Atrial Appendage Closure with Surgery trial were coded for known AF at baseline and for postoperative first-time AF diagnosis. AF occurrence was classified as follows: peri-procedural ≤7 days postoperatively, early >7 days but ≤3 months and late >3 months. Patients with no AF recurrence registered during follow-up were invited to undergo Holter monitoring. A total of 163 (86.2%) patients had no history of AF. Among these, 80 (49.1%) developed new-onset peri-procedural AF. After a mean follow-up of 3.7±1.6 years, late AF occurred in 35 of the 80 (43.8%) patients who developed peri-procedural AF and in 6 additional patients (7.2%) who remained in sinus rhythm until discharge (hazard ratio [HR] 9.3, 95% CI 3...Continue Reading

Citations

Dec 27, 2018·Current Opinion in Cardiology·Andrew C T HaSubodh Verma
Jun 27, 2019·European Heart Journal·Dipak Kotecha, Manuel Castellá
Feb 1, 2021·Cardiac Electrophysiology Clinics·Martin AguilarStanley Nattel
May 3, 2021·JACC. Clinical Electrophysiology·Sahar S AbdelmoneimJohn F Heitner

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Methods Mentioned

BETA
coronary artery bypass

Clinical Trials Mentioned

NCT02378116

Software Mentioned

SAS
LAACS

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