New oral and topical approaches for the treatment of melasma

International Journal of Women's Dermatology
Pearl E GrimesD Kwak

Abstract

Melasma is a common, therapeutically challenging, and universally relapsing disorder of hyperpigmentation that is most often observed in women and individuals with Fitzpatrick Skin Types III through VI. The pathogenesis of melasma is complex and protean. Contributing factors that are often implicated in the etiopathogenesis of this condition include a genetic predisposition, intense ultraviolet radiation exposure, and hormonal influences. Therapeutic interventions for melasma include a multimodality approach incorporating photoprotection agents, topical and oral skin lighteners, and resurfacing procedures. Given our expanding knowledge of the pathogenesis of melasma, new and effective treatments are expanding our therapeutic armamentarium. This article reviews new and emerging oral and topical treatments for melasma.

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Citations

Feb 25, 2021·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Ensaf M Abdel-MajidAmira A Abdel Motaleb
May 9, 2021·Journal of Complementary & Integrative Medicine·Kani JavedanMohammad Hosein Farzaei
Jun 12, 2021·The Journal of Dermatological Treatment·Sophia HuMona Sadeghpour
Sep 3, 2021·Lasers in Surgery and Medicine·Iwona MicekJustyna Gornowicz-Porowska
Jan 13, 2022·Journal of Cosmetic Dermatology·Naseem Ahmad Charoo

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