New paradigm for optical imaging: temporally encoded maps of intrinsic signal

Neuron
Valery A Kalatsky, Michael P Stryker

Abstract

We present a new technique for acquiring and analyzing intrinsic signal optical images of brain activity, using continuous stimulus presentation and data acquisition. The main idea is to present a temporally periodic stimulus and to analyze the component of the response at the stimulus frequency. Advantages of the new technique include the removal of heart, respiration, and vasomotor artifacts, a dramatic increase in spatial resolution, and a 30-fold or greater reduction in acquisition time. We also present a novel approach to localizing instantaneous neuronal responses using time-reversed stimuli that is widely applicable to brain imaging. To demonstrate the power of the technique, we present high-resolution retinotopic maps of five visual areas in mouse cortex and orientation maps in cat visual cortex.

References

Feb 29, 1980·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·S Zeki
Sep 1, 1980·The Journal of Comparative Neurology·E WagorA L Pearlman
Sep 1, 1980·The Journal of Comparative Neurology·N J Mangini, A L Pearlman
Dec 1, 1982·Experimental Neurology·J OlavarriaR C Van Sluyters
Jun 16, 1994·Nature·S A EngelM N Shadlen
Mar 19, 1996·Proceedings of the National Academy of Sciences of the United States of America·E A DeYoeJ Neitz
Aug 27, 2002·Nature Neuroscience·William H BoskingDavid Fitzpatrick
Dec 1, 1961·The Journal of Physiology·P M DANIEL, D WHITTERIDGE

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Citations

Jan 8, 2014·Proceedings of the National Academy of Sciences of the United States of America·Franziska GreifzuSiegrid Löwel
Sep 6, 2005·Proceedings of the National Academy of Sciences of the United States of America·Valery A KalatskyMichael P Stryker
Apr 22, 2014·Nature Neuroscience·Emmanouil FroudarakisAndreas S Tolias
Apr 6, 2011·Brain Structure & Function·Melissa PaulussenLutgarde Arckens
Jun 28, 2011·Brain, Behavior and Evolution·Leah KrubitzerDylan F Cooke
Feb 24, 2004·Annual Review of Physiology·Matthew L Williams, Walter J Koch
Dec 13, 2012·Brain Imaging and Behavior·Bin Tang, Valery A Kalatsky
Feb 22, 2005·Nature Neuroscience·Yoshiaki TagawaCarla J Shatz
Jun 1, 2005·Nature Neuroscience·Xin YuDaniel H Turnbull
Dec 6, 2005·Nature Neuroscience·Sonja B HoferMark Hübener
Feb 13, 2007·Nature Neuroscience·Spencer L Smith, Joshua T Trachtenberg
Aug 17, 2010·Nature Neuroscience·Spencer L Smith, Michael Häusser
Apr 12, 2011·Nature Neuroscience·Jerry L ChenElly Nedivi
Jul 31, 2012·Nature Neuroscience·Mariana M B CardosoAniruddha Das
May 28, 2016·Biomedical Optics Express·Hideyuki WatanabeManabu Tanifuji
Dec 10, 2014·Proceedings of the National Academy of Sciences of the United States of America·Yunshuo TangJuan Sebastian Espinosa
Sep 16, 2014·Experimental Gerontology·Sophia Katharina StodieckSiegrid Löwel
Dec 29, 2015·NeuroImage·Jérôme RibotJonathan Touboul
May 28, 2015·Proceedings of the National Academy of Sciences of the United States of America·Xiaojie HuangOliver M Schlüter
Aug 12, 2015·Proceedings of the National Academy of Sciences of the United States of America·Keerthi KrishnanZ Josh Huang
Feb 22, 2012·Optics Letters·Shin Ae KimSang Beom Jun
Aug 16, 2011·Trends in Neurosciences·Andrew D Huberman, Cristopher M Niell
Jul 5, 2011·Neural Networks : the Official Journal of the International Neural Network Society·Shigeru TanakaSeong-Gi Kim
Jun 15, 2011·Journal of Neuroscience Methods·Kentaroh TakagakiFrank W Ohl
Jan 19, 2010·Journal of Neuroscience Methods·Cynthia H Chen-BeeRon D Frostig
Mar 8, 2016·Nature Communications·G O SipeA K Majewska
Jul 17, 2012·Neuron·Amos GdalyahuJoshua T Trachtenberg
Apr 28, 2007·Trends in Neurosciences·Jean-Philippe Thivierge, Gary F Marcus

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