New perspectives in prostate cancer management

Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
Laurent Boccon-GibodP Richaud

Abstract

The treatment of prostate cancer is experiencing important innovations. Hormone therapy includes a new class of drugs: LHRH antagonists, which induce a rapid, fast and sustained reduction of testosterone levels. Active surveillance enables to avoid an aggressive treatment without decreasing survival, provided that strict eligibility and follow-up criteria are applied. New imaging techniques and laboratory assays lead to early diagnosis of small size tumors. Lastly, focal therapy has the potential to target localized cancers without deterioration of surrounding structures. These concomitant improvements offer the clinician and the patient attractive options for prostate cancer management. However, they are not devoid of limitations and constraints. Thus, it is crucial to define the most appropriate patient's profile for each therapeutic option, taking into account the objective characteristics of the tumor and the psychological features of the patient.

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Citations

Mar 28, 2016·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·G PloussardL Salomon
Dec 17, 2008·The Journal of Urology·Julien GuillotreauPascal Rischmann
Aug 12, 2014·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Manuel NistalMiguel Reyes-Múgica

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