New Perspectives Related to the Bioluminescent System in Dinoflagellates: Pyrocystis lunula , a Case Study

International Journal of Molecular Sciences
Carlos FajardoFrancisco Javier Fernandez-Acero

Abstract

Pyrocystis lunula is considered a model organism due to its bioluminescence capacity linked to circadian rhythms. The mechanisms underlying the bioluminescent phenomenon have been well characterized in dinoflagellates; however, there are still some aspects that remain an enigma. Such is the case of the presence and diversity of the luciferin-binding protein (LBP), as well as the synthesis process of luciferin. Here we carry out a review of the literature in relation to the molecular players responsible for bioluminescence in dinoflagellates, with particular interest in P. lunula. We also carried out a phylogenetic analysis of the conservation of protein sequence, structure and evolutionary pattern of these key players. The basic structure of the luciferase (LCF) is quite conserved among the sequences reported to date for dinoflagellate species, but not in the case of the LBP, which has proven to be more variable in terms of sequence and structure. In the case of luciferin, its synthesis has been shown to be complex process with more than one metabolic pathway involved. The glutathione S-transferase (GST) and the P630 or blue compound, seem to be involved in this process. In the same way, various hypotheses regarding the role of...Continue Reading

References

Jan 1, 1976·Journal of Cellular Physiology·R E SchmitterJ W Hastings
Jan 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·J A KooG B Schuster
Aug 15, 1988·Archives of Biochemistry and Biophysics·C Fresneau, B Arrio
Dec 1, 1986·Archives of Biochemistry and Biophysics·C FresneauP Volfin
Dec 1, 1972·Journal of Cellular Physiology·J P Hamman, H H Seliger
Jan 1, 1971·Archives of Biochemistry and Biophysics·M Fogel, J W Hastings
Apr 1, 1994·Plant Molecular Biology·S MachabéeD Morse
Aug 19, 1997·Proceedings of the National Academy of Sciences of the United States of America·L LiJ W Hastings
Jan 19, 1999·Annual Review of Cell and Developmental Biology·T Wilson, J W Hastings
Apr 13, 2002·Photochemistry and Photobiology·Hisashi MorishitaYoshihiro Ohmiya
Nov 26, 2003·Gene·O Keith Okamoto, J Woodland Hastings
Feb 10, 2004·Biochemical and Biophysical Research Communications·Hidetoshi AkimotoYoshihiro Ohmiya
Mar 23, 2004·Nucleic Acids Research·Robert C Edgar
Sep 2, 2004·Photochemistry and Photobiology·Naomi TanikawaYoshihiro Ohmiya
Nov 17, 2004·Proceedings of the National Academy of Sciences of the United States of America·Liyun LiuJ Woodland Hastings
Jan 25, 2005·Proceedings of the National Academy of Sciences of the United States of America·L Wayne SchultzJ Woodland Hastings
Jun 1, 2005·BMC Genomics·Jeremiah D HackettDebashish Bhattacharya
Jul 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·P Bennoun
Nov 30, 2006·Proceedings of the National Academy of Sciences of the United States of America·Liyun Liu, J Woodland Hastings
Jun 15, 2007·The Biological Bulletin·Elisa M Maldonado, Michael I Latz
Jul 9, 2008·Current Biology : CB·Claudio H Slamovits, Patrick J Keeling
Nov 20, 2008·The FEBS Journal·Nerino AllocatiCarmine Di Ilio
Oct 22, 2009·Biochemistry·Holly J Atkinson, Patricia C Babbitt
Dec 15, 2010·Annual Review of Marine Science·Steven H D HaddockJames F Case
Dec 21, 2010·The Journal of Biological Chemistry·Yasuo YamauchiYukihiro Sugimoto
Apr 26, 2011·Research in Microbiology·Senjie Lin
Oct 19, 2011·Proceedings of the National Academy of Sciences of the United States of America·Susan M E SmithThomas E Decoursey

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Datasets Mentioned

BETA
AF394059.1
AF394060.1
MN259726
MN259727
AAA29164.1
AAN85429.1

Software Mentioned

MEGA
MUSCLE
Phyre2
EzMol

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