New scaphocephaly severity indices of sagittal craniosynostosis: a comparative study with cranial index quantifications

The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association
Salvador Ruiz-CorreaA Hing

Abstract

To describe a novel set of scaphocephaly severity indices (SSIs) for predicting and quantifying head- and skull-shape deformity in children diagnosed with isolated sagittal synostosis (ISS) and compare their sensitivity and specificity with those of the traditional cranial index (CI). Computed tomography head scans were obtained from 60 patients diagnosed with ISS and 41 age-matched control patients. Volumetric reformations of the skull and overlying skin were used to trace two-dimensional planes defined in terms of skull-base plane and internal or surface landmarks. For each patient, novel SSIs were computed as the ratio of head width and length as measured on each of these planes. A traditional CI was also calculated and a receiver operating characteristic curve analysis was applied to compare the sensitivity and specificity of the proposed indices with those of CI. Although the CI is a sensitive measure of scaphocephaly, it is not specific and therefore not a suitable predictor of ISS in many practical applications. The SSI-A provides a specificity of 95% at a sensitivity level of 98%, in contrast with the 68% of CI. On average, the sensitivity and specificity of all proposed indices are superior to those of CI. Measurements...Continue Reading

Associated Clinical Trials

Feb 16, 2004·Matt Speltz

References

Mar 1, 1992·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·A A WaitzmanG E Pron
Jan 1, 1992·Plastic and Reconstructive Surgery·J C PosnickD Armstrong
Aug 1, 1988·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·G Kaiser
Sep 1, 1982·Neurosurgery·D J David, D A Simpson
Jan 1, 1995·Pediatric Neurosurgery·D N ThompsonR D Hayward
Mar 29, 1996·American Journal of Medical Genetics·E LajeunieD Renier
Mar 1, 1996·The Journal of Craniofacial Surgery·H FriedeA A Figueroa
Aug 1, 1996·Pediatric Neurosurgery·A L AlbrightB L Shultz
May 14, 1999·Plastic and Reconstructive Surgery·J PanchalS H Huang
Sep 9, 2000·Journal of Medical Genetics·W Reardon
May 19, 2001·The Journal of Craniofacial Surgery·J Guimarães-FerreiraC G Lauritzen
Jun 8, 2001·Plastic and Reconstructive Surgery·J J Fata, M S Turner
Jul 27, 2001·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·P ChristophisH P Howaldt
Jul 12, 2002·Statistics in Medicine·Xiao-Hua Zhou, Jaroslaw Harezlak
Sep 10, 2002·The Journal of Craniofacial Surgery·Kelly Seymour-DempseyJaime Gateno
Oct 30, 2003·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·José Guimarães-FerreiraClaes G K Lauritzen
Sep 4, 2004·The Journal of Craniofacial Surgery·Lisa R DavidLouis C Argenta

❮ Previous
Next ❯

Citations

Nov 21, 2007·Current Opinion in Pediatrics·Michael L Cunningham, Carrie L Heike
Dec 3, 2009·Plastic and Reconstructive Surgery·Jeffrey R MarcusSrinivasan Mukundan
Jun 24, 2010·Biomedical Engineering Online·Chia-Chi TengIra J Kalet
Sep 18, 2008·Neurosurgery·Salvador Ruiz-CorreaMichael L Cunningham
Sep 1, 2007·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Salvador Ruiz-CorreaMatthew L Speltz
Jun 27, 2014·Journal of Neurosciences in Rural Practice·Muhammad Awwal MusaHamid Ahmed
Mar 8, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Erik J van LindertWilfred A Borstlap
Aug 9, 2012·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Luca MassimiConcezio Di Rocco
Jun 27, 2014·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Junnu LeikolaMika Koivikko
Jun 26, 2012·The Journal of Pediatrics·Jan-Falco WilbrandHans-Peter Howaldt
Jan 9, 2016·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Kyu Won ShimYong Oock Kim
Jan 31, 2016·The Journal of Craniofacial Surgery·Shaheel ChummunDavid J David
Nov 7, 2009·Neonatal Network : NN·Linda Merritt
Jan 26, 2016·Annals of Plastic Surgery·Andrew SimpsonMichael Bezuhly
May 20, 2017·Journal of Neurosurgery. Pediatrics·Victoria KutaMichael Bezuhly
Jun 28, 2017·Plastic and Reconstructive Surgery·Jeffrey A FearonJohn Kolar
Jan 24, 2009·The Journal of Craniofacial Surgery·Raja Kummoona
Dec 2, 2010·The Journal of Craniofacial Surgery·Heidrun SchaafJan-Falco Wilbrand
Dec 12, 2018·The Journal of Craniofacial Surgery·Sultan Z Al-ShaqsiJohn Phillips
Jan 11, 2014·The Journal of Craniofacial Surgery·Mitchel SeruyaDavid K Chong
Dec 29, 2010·The Journal of Craniofacial Surgery·Leahthan F DomeshekJeffrey R Marcus
Mar 10, 2020·The Journal of Craniofacial Surgery·Sultan Z Al-ShaqsiJohn Phillips
Jul 10, 2014·The Journal of Craniofacial Surgery·Noopur GangopadhyayAlbert S Woo
Jun 14, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Rosalinda CalandrelliCesare Colosimo
Apr 28, 2016·Plastic and Reconstructive Surgery·Curtis S BergquistAnna A Kuang
Dec 13, 2018·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Brian Y HongChristopher R Forrest
Jul 20, 2019·Plastic and Reconstructive Surgery. Global Open·William X Z LiawWilliam Walsh
Apr 19, 2020·European Journal of Pediatrics·Otto D M KronigLéon N A Van Adrichem
Oct 19, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Otto D M KronigLéon N A Van Adrichem
Jan 17, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Jose Erasmo Dal'Col Lucio, Hamilton Matushita
May 10, 2016·The Journal of Craniofacial Surgery·Guangming ZhangXiaobo Zhou
Apr 23, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Matthieu VinchonAlexis Wolber
Feb 4, 2021·The Journal of Craniofacial Surgery·James MooneyJames Johnston
May 27, 2021·Plastic and Reconstructive Surgery. Global Open·Christopher D HughesIngrid M Ganske

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.