New Scheimpflug Dynamic In Vivo Curve Analyses to Characterize Biomechanical Changes of the Cornea After Cross-linking for Progressive Keratoconus

Journal of Refractive Surgery
Johannes SteinbergStephan J Linke

Abstract

To evaluate the effect of corneal cross-linking (CXL) in progressive keratoconus by applying in vivo static and dynamic Scheimpflug analyses. In this longitudinal retrospective study, corneal topography and tomography (Pentacam HD) and dynamic Scheimpflug-based biomechanical analyses (CorvisST [CST]) of 24 eyes of 24 patients with progressive keratoconus before and 6 months after CXL were reviewed. New dynamic curve analyses, provided by Oculus Optikgeräte, were performed to analyze corneal dynamics throughout the entire response to the CST air puff impulse. Besides subtle changes of topography and tomography, only the CorvisST predefined parameters peak distance (-0.5 mm) and radius of the intended cornea (+0.5 mm; P < .05) demonstrated statistically significant differences 6 months after CXL. Using new dynamic curve analyses, additional distinct changes of the corneal biomechanical characteristics after CXL were noted. Published results of corneal biomechanical changes after CXL for progressive keratoconus based on single, predefined CST parameters are inconsistent. The new dynamic curve analyses demonstrate distinct changes of the biomechanical properties of the cornea and might therefore be the next step in understanding in...Continue Reading

References

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Citations

Dec 12, 2017·Journal of Refractive Surgery·Riccardo VinciguerraStephen B Kaye
May 6, 2016·Cornea·Johannes Steinberg, Stephan J Linke
May 26, 2017·International Ophthalmology·Nehir İnceoğluMahmut Oğuz Ulusoy
Jul 28, 2020·European Journal of Ophthalmology·Mahmoud JabbarvandAlireza Jamali
Jul 14, 2019·Journal of Biomechanics·Hassan HashemiSoheila Asgari

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