New Self-Expanding Transcatheter Aortic Valve Device for Transfemoral Implantation- Early Results of the First-in-Asia Implantation of the ACURATE Neo/TF(TM) System

Circulation Journal : Official Journal of the Japanese Circulation Society
Koichi MaedaYoshiki Sawa

Abstract

Feasibility and early results of transfemoral aortic valve implantation using the ACURATE neo/TF(TM)self-expanding stent are reported. The study group of 15 patients (mean age 83.3±6.0) was enrolled with a mean EuroSCORE and STS score of 21.9±11.6% and 7.5±3.1%, respectively. Clinical and echocardiographic evaluations were performed at baseline, discharge, 30 days and 6 months. The primary endpoint was all-cause mortality at 30 days. Transcatheter aortic valve implantation (TAVI) using the ACURATE neo/TF device was successful in 14 patients; 1 patient underwent valve-in-valve implantation because the prosthetic valve embolized during withdrawal of the delivery system. Conversion to surgery, coronary obstruction, peri-operative stroke, and pacemaker implantation did not occur at 30 days. Mean transvalvular gradients at discharge significantly decreased from 44.2±10.5 mmHg (preprocedural) to 7.7±3.1 mmHg (P<0.0001) and effective orifice area significantly increased from 0.77±0.12 to 1.69±0.25 cm(2)(P<0.0001). None or trace paravalvular leak was revealed in 50.0%, and no patient exhibited moderate or higher paravalvular leak. The overall mortality at 30 days and 6 months was 0% and 6.7%, respectively. A new self-expanding TF TAVI ...Continue Reading

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Citations

Sep 29, 2015·Expert Review of Cardiovascular Therapy·Antonio MangieriAzeem Latib
Jan 9, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Tomohiko TaniguchiTakeshi Kimura
Dec 24, 2015·Future Cardiology·Usaid K AllahwalaRavinay Bhindi
May 12, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Toyoaki Murohara
Jun 13, 2016·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Alec VahanianJohn Webb
Aug 9, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Junjiro KobayashiAtsushi Okada
Jan 27, 2017·Circulation Journal : Official Journal of the Japanese Circulation Society·Yasuhiro IchiboriYasushi Sakata
Jan 17, 2017·Expert Review of Medical Devices·Marco BarbantiCorrado Tamburino
Dec 21, 2016·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Hiroki TateishiFabio S de Brito
Dec 29, 2016·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Tannas JateneJ Eduardo Sousa
Sep 30, 2016·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Rodrigo BagurMichael W A Chu
Feb 11, 2018·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Hideki Oshima
Jan 21, 2017·Postgraduate Medical Journal·Sofia MetaxaConstantinos G Missouris
Dec 6, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Shinya TakimotoTakeshi Kimura
Oct 2, 2015·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Nicola CorcioneArturo Giordano
Sep 19, 2015·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Marina Urena, Josep Rodés-Cabau

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