PMID: 11320852Apr 26, 2001Paper

New strategies for the postsurgical treatment of malignant glioma

Recenti progressi in medicina
A Boiardi

Abstract

Malignant gliomas are known for their intrinsic heterogeneity that contributes to tumour recurrence, despite aggressive multimodality therapy. New approaches of post surgical treatment are formulated, according to specific aspects of the biology of gliomas including angiogenesis, invasion, DNA-repair mechanisms, cell cycle regulation and apoptosis. Efforts are also done in order to define the use of currently available cytotoxic agents by combining them with so-called biologic modalities. Thus there has been a change in the concept of management of malignant gliomas focusing the aim in containing the tumour, rather than attempting a cure.

Related Concepts

Related Feeds

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Related Papers

Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
J Bourhis, E Lartigau
European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
Giovanna Damia, Maurizio D'Incalci
Survey of Ophthalmology
Olga Golubnitschaja, Josef Flammer
Journal of Biological Regulators and Homeostatic Agents
M A Benotmane
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]
C Streffer
© 2021 Meta ULC. All rights reserved