New terpenes from Salvia palaestina Benth. and Salvia syriaca L. growing wild in Jordan

Journal of Asian Natural Products Research
Hala I Al-JaberMusa H Abu Zarga

Abstract

The novel seco-ursane-type triterpenoid 3β,11α-dihydroxy-17,22-seco-17(28), 12-ursadien-22-oic acid (1) was isolated for the first time from a natural source from two Salvia species growing wild in Jordan, Salvia palaestina Benth. and Salvia syrica L. In addition to compound 1, S. syriaca afforded a new sesquiterpene named syriacine (2). S. palaestina also afforded 15 other known compounds, 6 of which are isolated for the first time from the plant, and these include velutin, hyptadienic acid, cirsilineol, 2α,3β-dihydroxyurs-12-en-28-oic acid, 2α,3α-dihydroxy-24-nor-4(23),12-oleanan-28-oic acid, and 2α,3β,24-trihydroxyurs-12-en-28-oic acid. S. syriaca also afforded 16 other known compounds, 7 of which are isolated for the first time from the plant. These are 1α,3α-dihydroxyolean-9(11),12-diene, maslinic acid, 2α,3β,24-trihydroxyolean-12-en-28-oic acid, 11-oxo-oleanolic acid, 11-oxo-ursolic acid, poriferast-5-en-3,7-diol, and pectolinangenin.

References

Nov 1, 1983·Journal of Natural Products·M MiskiT J Mabry
Jan 26, 2002·Phytochemistry·Yinrong Lu, L Yeap Foo
Feb 7, 2002·Phytochemistry·Shoko TaniguchiTakashi Yoshida
Oct 26, 2002·Journal of Natural Products·María C Ballesta-AcostaBenjamín Rodríguez
Mar 28, 2006·Journal of Natural Products·Gülaçti Topçu
May 6, 2006·Phytotherapy Research : PTR·Giovina FioreLucia Micheli
Jan 15, 2008·Phytochemistry·Giuseppina CioffiNunziatina De Tommasi

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Citations

Oct 25, 2014·Natural Product Reports·Robert A Hill, Joseph D Connolly
Sep 17, 2014·Natural Product Research·Amal M F Al-AboudiMonther A Khanfar
Sep 16, 2016·Natural Product Research·Mohammed B Al-BarhamMusa H Abu Zarga
Mar 25, 2017·Natural Product Research·Mahmoud A Al-QudahSultan T Abu Orabi
Jun 5, 2019·Natural Product Research·Mahmoud A Al-QudahSultan T Abu Orabi
Jul 26, 2013·Natural Product Reports·Braulio M Fraga
Dec 24, 2019·Chemistry & Biodiversity·Hala I Al-JaberMusa H Abu Zarga
Jun 15, 2018·Molecular Medicine Reports·Qasem AbdallahAmin Abdulmajid
May 6, 2020·Natural Product Reports·Aldo AlmeidaSøren Bak
Dec 30, 2020·Phytochemistry·Sayyedeh Fatemeh AskariSamira Eghbali
Apr 22, 2021·Journal of Asian Natural Products Research·Musa H Abu ZargaAmal M F Al-Aboudi
Apr 27, 2021·Natural Product Research·Lina M BarhoumiMusa H Abu Zarga

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