New therapies for controlling atopic itch

The Journal of Dermatology
Masutaka Furue, Takafumi Kadono

Abstract

Chronic itch in atopic dermatitis markedly diminishes the quality of life of affected individuals. Sleep disturbance and impaired productivity in work due to chronic itch impose a socioeconomic burden. Conventional therapies for atopic dermatitis are capable of reducing atopic itch. However, the majority of patients are not satisfied with the antipruritic capacity of conventional treatments. In this review, we summarize recent progress in itch signaling in the skin, dorsal root ganglion and spinal cord. New therapies for controlling atopic itch are also discussed.

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Citations

Mar 29, 2016·Geriatrics & Gerontology International·Ryoji Tanei, Yasuko Hasegawa
Dec 6, 2017·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Takeshi NakaharaMasutaka Furue
Oct 27, 2017·Expert Opinion on Investigational Drugs·Masutaka FurueTakeshi Nakahara
Jun 27, 2018·Pediatric Dermatology·Emily BoozalisShawn G Kwatra
May 23, 2020·International Journal of Molecular Sciences·Michela CampoloEmanuela Esposito
Jun 18, 2017·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Masutaka Furue, Takafumi Kadono
Oct 30, 2020·The Journal of Dermatology·Takeshi NakaharaMasutaka Furue
Dec 2, 2020·Progress in Lipid Research·Hiroshi Ueda
Apr 4, 2021·International Journal of Molecular Sciences·Roberto MaglieFrancesco De Logu
May 1, 2021·Journal of Clinical Medicine·Masutaka Furue, Mihoko Furue

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Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

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